Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1. - Wikidata - awgldk - TriplyDB

Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.

Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.

http://www.wikidata.org/entity/Q37648758

about

VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.

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Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.

http://www.wikidata.org/entity/Q37648758

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 13 May 2012

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@en

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@nl

type

label

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@en

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@nl

prefLabel

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@en

Murine toxicology and pharmaco ...... ocking agent (RAMBA), VN/12-1.

@nl

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S00280-012-1877-Z

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Cancer Chemotherapy and Pharmacology

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Murine toxicology and pharmaco ...... locking agent (RAMBA), VN/12-1

@en

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Abhijit M Godbole

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Marlena S Martin

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Puranik Purushottamachar

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P2860

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth.

Cytochrome p450 retinoic acid 4-hydroxylase inhibitors: potential agents for cancer therapy.

Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases.

MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours.

Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice.

Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts.

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

RAR and RXR modulation in cancer and metabolic disease.

Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenografts

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s00280-012-1877-z

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339-344

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scholarly article

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10.1007/S00280-012-1877-Z

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2

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2012-05-13T00:00:00Z

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22580781

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3959742

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