Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons. - Wikidata - awgldk - TriplyDB

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

http://www.wikidata.org/entity/Q37649071

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Molecular Mechanisms of Neurodegeneration in Spinal Muscular Atrophy Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast.Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins Human defensins facilitate local unfolding of thermodynamically unstable regions of bacterial protein toxins.Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse ZFIN, The zebrafish model organism database: Updates and new directions.Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype Retrocyclins neutralize bacterial toxins by potentiating their unfolding.Fishing for causes and cures of motor neuron disorders.Genetic modifiers and oligogenic inheritance.PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.Recent Discoveries in Monogenic Disorders of Childhood Bone Fragility.Advances in understanding the role of disease-associated proteins in spinal muscular atrophy.A novel splice mutation in PLS3 causes X-linked early onset low-turnover osteoporosis.The Actin Cytoskeleton in SMA and ALS: How Does It Contribute to Motoneuron Degeneration?Plastin 3 is upregulated in iPSC-derived motoneurons from asymptomatic SMN1-deleted individuals.Differentiation defects in primary motoneurons from a SMARD1 mouse model that are insensitive to treatment with low dose PEGylated IGF1 Gender Effects on the Clinical Phenotype in Japanese Patients with Spinal Muscular Atrophy.A novel large fragment deletion in PLS3 causes rare X-linked early-onset osteoporosis and response to zoledronic acid.Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy.Axon outgrowth and neuronal differentiation defects after a-SMN and FL-SMN silencing in primary hippocampal cultures.

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P2860

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

http://www.wikidata.org/entity/Q37649071

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@en

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@nl

type

label

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@en

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@nl

prefLabel

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@en

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@nl

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Human Molecular Genetics

P1476

Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons.

@en

P2093

Alison N Lyon

http://www.w3.org/2001/XMLSchema#string

Christine E Beattie

http://www.w3.org/2001/XMLSchema#string

Dmitri S Kudryashov

http://www.w3.org/2001/XMLSchema#string

Elena Kudryashova

http://www.w3.org/2001/XMLSchema#string

Ricardo H Pineda

http://www.w3.org/2001/XMLSchema#string

le Thi Hao

http://www.w3.org/2001/XMLSchema#string

P2860

A novel protein with RNA-binding motifs interacts with ataxin-2

Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney

Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking

Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways

Phosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells

Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts

A positive modifier of spinal muscular atrophy in the SMN2 gene

Functional differences between L- and T-plastin isoforms

Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins

A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation.

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1990-2004

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10.1093/HMG/DDT595

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8

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23

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2013-11-23T00:00:00Z

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258854921

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24271012

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3959813

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