High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons.
about
A gain-of-function mutation in STAT6Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus InfectionA novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expressionRIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteinsThe p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral stateKinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animalsCloning and functional characterization of a mammalian zinc transporter that confers resistance to zincCollaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genesThe amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptorInterferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factorsSignaling advances from immunogenetics to immunogenomicsA GFP-based reporter system to monitor nonsense-mediated mRNA decayADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus EntryResistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and VirulenceTRAIL Is a Novel Antiviral Protein against Dengue VirusFocal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesionEnhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKRDifferential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7Transcriptional silencing of perlecan gene expression by interferon-gammaHIV-1 and its gp120 inhibits the influenza A(H1N1)pdm09 life cycle in an IFITM3-dependent fashionThe LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activitiesY-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effectsRecruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 proteinExpression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.Sendai virus and simian virus 5 block activation of interferon-responsive genes: importance for virus pathogenesisInduction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1.Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 proteinSingle amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cellsThe leader protein of Theiler's virus inhibits immediate-early alpha/beta interferon production.Replication of Toxoplasma gondii, but not Trypanosoma cruzi, is regulated in human fibroblasts activated with gamma interferon: requirement of a functional JAK/STAT pathwayInterferon regulatory factor 7 is negatively regulated by the Epstein-Barr virus immediate-early gene, BZLF-1Suppression of growth by all-trans retinoic acid requires prolonged induction of interferon regulatory factor 1 in cervical squamous carcinoma (SiHa) cells.Apical role for BRG1 in cytokine-induced promoter assemblySTAT1 from the cell membrane to the DNA.Janus kinases: components of multiple signaling pathways.Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.
P2860
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P2860
High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@en
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@nl
type
label
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@en
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@nl
prefLabel
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@en
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@nl
P2093
P2860
P4510
P356
P1476
High-frequency mutagenesis of ...... h alpha and gamma interferons.
@en
P2093
P2860
P304
11455-11459
P356
10.1073/PNAS.88.24.11455
P407
P577
1991-12-01T00:00:00Z