Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts.
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Targets for therapy in sarcomeric cardiomyopathiesRestitution slope is principally determined by steady-state action potential duration.Icariin, a Novel Blocker of Sodium and Calcium Channels, Eliminates Early and Delayed Afterdepolarizations, As Well As Triggered Activity, in Rabbit CardiomyocytesPharmacology and Toxicology of Nav1.5-Class 1 anti-arrhythmic drugs.Tolterodine reduces veratridine-augmented late INa, reverse-INCX and early afterdepolarizations in isolated rabbit ventricular myocytes.Inhibition of Late Sodium Current as an Innovative Antiarrhythmic Strategy.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets.Image-based motion correction for optical mapping of cardiac electrical activity.Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension.The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model.Use-Dependent Block of Human Cardiac Sodium Channels by GS967.Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy
P2860
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P2860
Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
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2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Selective inhibition of late s ...... illation in intact rat hearts.
@en
Selective inhibition of late s ...... illation in intact rat hearts.
@nl
type
label
Selective inhibition of late s ...... illation in intact rat hearts.
@en
Selective inhibition of late s ...... illation in intact rat hearts.
@nl
prefLabel
Selective inhibition of late s ...... illation in intact rat hearts.
@en
Selective inhibition of late s ...... illation in intact rat hearts.
@nl
P2093
P2860
P1433
P1476
Selective inhibition of late s ...... illation in intact rat hearts.
@en
P2093
Arash Pezhouman
Hayk Ghukasyan
Hayk Stepanyan
Hrayr S Karagueuzian
Luiz Belardinelli
Sepideh Madahian
P2860
P304
P356
10.1016/J.HRTHM.2013.11.026
P577
2013-11-28T00:00:00Z