B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.
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Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein CrkSite-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxisIdentification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gammaFunctions of the major tyrosine phosphorylation site of the PDGF receptor beta subunitExpression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression systemStructural and functional studies on platelet-derived growth factorTyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationPDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fateFunctional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain CalcificationChemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmanninDemonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptorsc-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGFNeuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells.A novel flow bioreactor for in vitro microvascularization.Regulation of macropinocytosis by p21-activated kinase-1PDGF induced microRNA alterations in cancer cells.Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas.Beta-actin mRNA localization is regulated by signal transduction mechanisms.Immunohistochemical expression of platelet-derived growth factor receptors in ovarian cancer patients with long-term follow-up.Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase.Mechanistic insights into the regulation of circular dorsal ruffle formation.Platelet-derived growth factor in glioblastoma-driver or biomarker?Variability in Platelet-Derived Growth Factor Receptor Alpha Antibody Specificity May Impact Clinical Utility of Immunohistochemistry Assays.Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights.Activated human hepatic stellate cells promote growth of human hepatocellular carcinoma in a subcutaneous xenograft nude mouse model.PDGF-BB triggered cytoplasmic calcium responses in cells with endogenous or stably transfected PDGF beta-receptors.Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB.Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.Functional co-operation between the subunits in heterodimeric platelet-derived growth factor receptor complexes.Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42.PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.Reversion of autocrine transformation by a dominant negative platelet-derived growth factor mutant.Ligand-induced homo- and hetero-dimerization of platelet-derived growth factor alpha- and beta-receptors in intact cells.Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF.Platelet-derived growth factor (PDGF)-induced activation of signal transducer and activator of transcription (Stat) 5 is mediated by PDGF beta-receptor and is not dependent on c-src, fyn, jak1 or jak2 kinases.
P2860
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P2860
B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@en
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@nl
type
label
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@en
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@nl
prefLabel
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@en
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@nl
P2093
P2860
P356
P1476
B-type receptor for platelet-d ...... eptor protein-tyrosine kinase.
@en
P2093
Claesson-Welsh L
Siegbahn A
P2860
P304
P356
10.1073/PNAS.87.1.128
P407
P577
1990-01-01T00:00:00Z