Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. - Wikidata - awgldk - TriplyDB

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

http://www.wikidata.org/entity/Q37659987

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Synthetic high-density lipoprotein-like nanoparticles as cancer therapy Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference Therapeutic targeting of liver inflammation and fibrosis by nanomedicine Delivery of oligonucleotides with lipid nanoparticles Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging Liver-targeted gene therapy: Approaches and challenges Screening of efficient siRNA carriers in a library of surface-engineered dendrimers Penetrating the Blood-Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles.mRNA vaccine delivery using lipid nanoparticles.In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease.Biogenic selenium nanoparticles induce ROS-mediated necroptosis in PC-3 cancer cells through TNF activation.Switchable Lipids: Conformational Change for Fast pH-Triggered Cytoplasmic Delivery.Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy.Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model.Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery Focused Library Approach to Discover Discrete Dipeptide Bolaamphiphiles for siRNA Delivery Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells Synthetic high-density lipoprotein-like nanoparticles for cancer therapy Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.High-Density Lipoproteins for Therapeutic Delivery Systems.Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature.RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.Accelerating the Translation of Nanomaterials in Biomedicine.Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery.Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo.Design and development of effective siRNA delivery vehicles.RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver.Future nanomedicine for the diagnosis and treatment of osteoarthritis Lipid nanoparticles for gene delivery.Peptide-based vectors: recent developments.Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment.Enhancing the pharmacokinetic/pharmacodynamic properties of therapeutic nucleotides using lipid nanoparticle systems.Targeted endothelial nanomedicine for common acute pathological conditions.Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA.Current views on inducing synthetic lethal RNAi responses in the treatment of cancer.Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.Properties of Native High-Density Lipoproteins Inspire Synthesis of Actively Targeted In Vivo siRNA Delivery Vehicles.Biodegradable Amino-Ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo.

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P2860

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

http://www.wikidata.org/entity/Q37659987

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 10 February 2014

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

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Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

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type

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Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

@en

Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

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Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

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Lipopeptide nanoparticles for ...... rodents and nonhuman primates.

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PNAS.1322937111

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Lipopeptide nanoparticles for ...... rodents and nonhuman primates

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P2093

Akin Akinc

http://www.w3.org/2001/XMLSchema#string

Arturo J Vegas

http://www.w3.org/2001/XMLSchema#string

Carmen Barnes

http://www.w3.org/2001/XMLSchema#string

Christopher A Alabi

http://www.w3.org/2001/XMLSchema#string

Daniel G Anderson

http://www.w3.org/2001/XMLSchema#string

Daniel J Siegwart

http://www.w3.org/2001/XMLSchema#string

Delai Chen

http://www.w3.org/2001/XMLSchema#string

Gaurav Sahay

http://www.w3.org/2001/XMLSchema#string

Hao Yin

http://www.w3.org/2001/XMLSchema#string

J Robert Dorkin

http://www.w3.org/2001/XMLSchema#string

P2860

The promises and pitfalls of RNA-interference-based therapeutics

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Genetic heterogeneity in human disease

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.

Lipid-like materials for low-dose, in vivo gene silencing

A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells.

Lipophilic peptides for gene delivery.

An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNA.

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

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3955-3960

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scholarly article

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10.1073/PNAS.1322937111

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11

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111

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Abigail Lytton-Jean

Robert Samuel Langer, Jr.

Karsten T Olejnik

Victor Koteliansky

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2014-02-10T00:00:00Z

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260154644

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24516150

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3964096

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