Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche.

Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche.

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http://www.wikidata.org/entity/Q37662690
Modelling clinical systemic lupus erythematosus: similarities, differences and success storiesPathogenesis of renal disease in systemic lupus erythematosus--the role of autoantibodies and lymphocytes subset abnormalitiesThe pathogenesis, diagnosis and treatment of lupus nephritis.Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone marrow and spinal cord while preserving peripheral regulatory mechanisms.Long-lived plasma cells are early and constantly generated in New Zealand Black/New Zealand White F1 mice and their therapeutic depletion requires a combined targeting of autoreactive plasma cells and their precursors.Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice.New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndromeSmall Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus.Autoreactive CD19+CD20- Plasma Cells Contribute to Disease Severity of Experimental Autoimmune Encephalomyelitis.HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus.Extensively re-organized systemic lymph nodes provide a feasible environment for self-reactivity in lupus-prone NZB × NZW F1 mice.
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Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche.

Item
http://www.wikidata.org/entity/Q37662690
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Long-term B cell depletion in ...... the kidney plasma cell niche.
@en
Long-term B cell depletion in ...... the kidney plasma cell niche.
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type
label
Long-term B cell depletion in ...... the kidney plasma cell niche.
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Long-term B cell depletion in ...... the kidney plasma cell niche.
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prefLabel
Long-term B cell depletion in ...... the kidney plasma cell niche.
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Long-term B cell depletion in ...... the kidney plasma cell niche.
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Long-term B cell depletion in ...... the kidney plasma cell niche.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932