Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span.

Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span.

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http://www.wikidata.org/entity/Q37670847
Biochemical Genetic Pathways that Modulate Aging in Multiple SpeciesThe somatotropic axis and longevity in miceAssociation between risk factors for vascular dementia and adiponectin.hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signalingDiminished mTOR signaling: a common mode of action for endocrine longevity factors.Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.Reductions in serum IGF-1 during aging impair health span.Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-IIGF-1 Receptor Insufficiency Leads to Age-Dependent Attenuation of Osteoblast Differentiation.Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice.Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice.The somatotropic axis and aging: Benefits of endocrine defects.Life-span Extension With Reduced Somatotrophic Signaling: Moderation of Aging Effect by Signal Type, Sex, and Experimental Cohort.Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in C. elegans models.Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging.Long-lived weight-reduced αMUPA mice show higher and longer maternal-dependent postnatal leptin surge.Regulation of reproduction and longevity by nutrient-sensing pathways.
P2860

Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span.

Item
http://www.wikidata.org/entity/Q37670847
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mice producing reduced levels ...... imum, but not mean, life span.
@en
Mice producing reduced levels ...... imum, but not mean, life span.
@nl
type
label
Mice producing reduced levels ...... imum, but not mean, life span.
@en
Mice producing reduced levels ...... imum, but not mean, life span.
@nl
prefLabel
Mice producing reduced levels ...... imum, but not mean, life span.
@en
Mice producing reduced levels ...... imum, but not mean, life span.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Mice producing reduced levels ...... imum, but not mean, life span.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932