Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.
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Endoglin in liver fibrogenesis: Bridging basic science and clinical practiceModulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer.Basis for substrate recognition and distinction by matrix metalloproteinasesEndoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial AutophagyRelease of endothelial cell associated VEGFR2 during TGF-β modulated angiogenesis in vitroAn engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy.A matrix metalloproteinase inhibitor enhances anti-cytotoxic T lymphocyte antigen-4 antibody immunotherapy in breast cancer by reprogramming the tumor microenvironmentHeart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling.Effects of the combination of TRC105 and bevacizumab on endothelial cell biology.Endoglin in human liver disease and murine models of liver fibrosis - a protective factor against liver fibrosis.Differential protective effects of connective tissue growth factor against Aβ neurotoxicity on neurons and glia.Endoglin and alk1 as therapeutic targets for hereditary hemorrhagic telangiectasia.Antagonizing CD105 enhances radiation sensitivity in prostate cancer.Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia
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Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 September 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Antibody-directed coupling of ...... regulation of TGF-β signaling.
@en
Antibody-directed coupling of ...... regulation of TGF-β signaling.
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type
label
Antibody-directed coupling of ...... regulation of TGF-β signaling.
@en
Antibody-directed coupling of ...... regulation of TGF-β signaling.
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prefLabel
Antibody-directed coupling of ...... regulation of TGF-β signaling.
@en
Antibody-directed coupling of ...... regulation of TGF-β signaling.
@nl
P2093
P2860
P356
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Antibody-directed coupling of ...... regulation of TGF-β signaling.
@en
P2093
J C Bloodworth
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P2888
P304
P356
10.1038/ONC.2013.386
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P577
2013-09-30T00:00:00Z
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P6179
1025649013