Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans. - Wikidata - awgldk - TriplyDB

Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.

Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.

http://www.wikidata.org/entity/Q37674725

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Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression Gastric cancer stem cells: a novel therapeutic target Diagnosis and management of high risk group for gastric cancer Helicobacter pylori infection induced gastric cancer; advance in gastric stem cell research and the remaining challenges Gastrokines: stomach-specific proteins with putative homeostatic and tumor suppressor roles.A unified model of the hierarchical and stochastic theories of gastric cancer.Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG)Genomic single nucleotide polymorphisms in the offspring of gastric cancer patients predispose to spasmolytic polypeptide-expressing metaplasia after H. pylori infection.Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer.Ndrg2 promoter hypermethylation triggered by helicobacter pylori infection correlates with poor patients survival in human gastric carcinoma TFF2-CXCR4 Axis Is Associated with BRAF V600E Colon Cancer.Dissecting DNA hypermethylation in cancer.CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer.Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells.Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.Mouse models of gastric cancer.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation.Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine.Gastric cancer-molecular and clinical dimensions.IL33 Is a Stomach Alarmin That Initiates a Skewed Th2 Response to Injury and Infection.Mouse models for gastric cancer: Matching models to biological questions.Inflammasomes in Inflammation-Induced Cancer.Promoter hypermethylation and downregulation of trefoil factor 2 in human gastric cancer.Stat3: linking inflammation to (gastrointestinal) tumourigenesis.Epigenetic modifications induced by Helicobacter pylori infection through a direct microbe-gastric epithelial cells cross-talk.Modifiable risk factors in periodontal disease: epigenetic regulation of gene expression in the inflammatory response.Linking immunity, epigenetics, and cancer in inflammatory bowel disease.Helicobacter pylori infection and stem cells at the origin of gastric cancer.Helicobacter pylori Induces Hypermethylation of CpG Islands Through Upregulation of DNA Methyltransferase: Possible Involvement of Reactive Oxygen/Nitrogen Species Helicobacter pylori DNA methyltransferases and the epigenetic field effect in cancerization Loss of Trefoil Factor 2 From Pancreatic Duct Glands Promotes Formation of Intraductal Papillary Mucinous Neoplasms in Mice.Trefoil factor family 2 expression inhibits gastric cancer cell growth and invasion in vitro via interactions with the transcription factor Sp3.Inflammasome Activation by Helicobacter pylori and Its Implications for Persistence and Immunity.How host regulation of Helicobacter pylori-induced gastritis protects against peptic ulcer disease and gastric cancer.

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Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.

http://www.wikidata.org/entity/Q37674725

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scientific article published on 27 August 2010

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Helicobacter pylori infection ...... evelopment in mice and humans.

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Helicobacter pylori infection ...... evelopment in mice and humans.

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Helicobacter pylori infection ...... evelopment in mice and humans.

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Helicobacter pylori infection ...... evelopment in mice and humans.

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Helicobacter pylori infection ...... evelopment in mice and humans.

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Helicobacter pylori infection ...... evelopment in mice and humans.

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J.GASTRO.2010.08.043

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Gastroenterology

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Helicobacter pylori infection ...... development in mice and humans

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Andrew S Giraud

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Anthony J Peterson

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Eng Kok Ong

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Kazuyuki Kawakami

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Louise O'Connor

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Toshinari Minamoto

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P2860

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

Autoinduction of the trefoil factor 2 (TFF2) promoter requires an upstream cis-acting element

A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa

Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses

Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production

Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein

TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury

Accelerated progression of gastritis to dysplasia in the pyloric antrum of TFF2 -/- C57BL6 x Sv129 Helicobacter pylori-infected mice

The gastrins: their production and biological activities.

Trefoil peptides are early markers of gastrointestinal maturation in the rat.

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2005-2017

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scholarly article

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10.1053/J.GASTRO.2010.08.043

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6

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Anna K. Walduck

Trevelyan R Menheniott

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2010-08-27T00:00:00Z

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46035439

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20801119

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Helicobacter pylori

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3970568

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