A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms.
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Structure-antiproliferative activity studies on l-proline- and homoproline-4-N-pyrrolidine-3-thiosemicarbazone hybrids and their nickel(ii), palladium(ii) and copper(ii) complexes.Copper(ii) thiosemicarbazone complexes induce marked ROS accumulation and promote nrf2-mediated antioxidant response in highly resistant breast cancer cells.Ribonucleotide reductase metallocofactor: assembly, maintenance and inhibition.Strong effect of copper(II) coordination on antiproliferative activity of thiosemicarbazone-piperazine and thiosemicarbazone-morpholine hybrids.Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53.Clinical pharmacology and clinical trials of ribonucleotide reductase inhibitors: is it a viable cancer therapy?A Phase I Study of Topotecan, Carboplatin and the PARP Inhibitor Veliparib in Acute Leukemias, Aggressive Myeloproliferative Neoplasms, and Chronic Myelomonocytic Leukemia.Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics.The thiosemicarbazone MeNNMe induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition
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A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A phase II trial of sequential ...... myeloproliferative neoplasms.
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A phase II trial of sequential ...... myeloproliferative neoplasms.
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type
label
A phase II trial of sequential ...... myeloproliferative neoplasms.
@en
A phase II trial of sequential ...... myeloproliferative neoplasms.
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prefLabel
A phase II trial of sequential ...... myeloproliferative neoplasms.
@en
A phase II trial of sequential ...... myeloproliferative neoplasms.
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P2093
P2860
P1433
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A phase II trial of sequential ...... myeloproliferative neoplasms.
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P2093
Amanda L Blackford
B Douglas Smith
Hetty E Carraway
Ivana Gojo
Jacqueline M Greer
Joshua F Zeidner
Judith E Karp
Keith W Pratz
Mark J Levis
Michael A McDevitt
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P304
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10.3324/HAEMATOL.2013.097246
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2013-12-20T00:00:00Z