Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
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Genes and chronic obstructive pulmonary diseaseOncostatin M is a potent stimulator of alpha1-antitrypsin secretion in lung epithelial cells: modulation by transforming growth factor-beta and interferon-gammaIdentification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes.Differential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids.Stable expression and cell-specific chromatin structure of human alpha1-antitrypsin cosmid transgenes in rat hepatoma cells.Cell-specific expression of alpha 1-antitrypsin in human intestinal epithelium.The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes.Cell-specific involvement of HNF-1beta in alpha(1)-antitrypsin gene expression in human respiratory epithelial cells.Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadridCytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.Evaluation of "at risk" alpha 1-antitrypsin genotype SZ with synthetic oligonucleotide gene probesMultiple tissues express alpha 1-antitrypsin in transgenic mice and man.Alpha 1-antitrypsin deficiency caused by the alpha 1-antitrypsin Nullmattawa gene. An insertion mutation rendering the alpha 1-antitrypsin gene incapable of producing alpha 1-antitrypsinInterferon beta 2/interleukin 6 modulates synthesis of alpha 1-antitrypsin in human mononuclear phagocytes and in human hepatoma cells.Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver diseaseRegulation of alpha 1 proteinase inhibitor function by rabbit alveolar macrophages. Evidence for proteolytic rather than oxidative inactivationDivergent expression of alpha1-protease inhibitor genes in mouse and humanAlpha 1-antitrypsin does not inhibit human monocyte caspase-1Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.Constitutive and modulated expression of the human alpha 1 antitrypsin gene. Different transcriptional initiation sites used in three different cell types.Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiencyRisk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.Alpha 1-antitrypsin is present within the primary granules of human polymorphonuclear leukocytes.Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits.A fast-acting elastase inhibitor in human monocytes.Plasminogen activator-specific inhibitors produced by human monocytes/macrophages.The inhibitory complex of human alpha 1-proteinase inhibitor and human leukocyte elastase is a neutrophil chemoattractant.Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele.The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency.Identification of differentially secreted biomarkers using LC-MS/MS in isogenic cell lines representing a progression of breast cancer.Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individualsAnalysis of effects of lipopolysaccharide and interferon on murine macrophages: modulation of elastase secretion in vitro.Alpha-1 antitrypsin gene exon use in stimulated lymphocytes.Inhibition of intracellular degradation increases secretion of a mutant form of alpha1-antitrypsin associated with profound deficiency.alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies.The cellular defect in alpha 1-proteinase inhibitor (alpha 1-PI) deficiency is expressed in human monocytes and in Xenopus oocytes injected with human liver mRNA.α(1)-antitrypsin deficiency and inflammation.Human monocyte activation by cleaved form of alpha-1-antitrypsin involvement of the phagocytic pathway.alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage.
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Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@en
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@nl
type
label
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@en
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@nl
prefLabel
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@en
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@nl
P2093
P2860
P356
P1476
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages.
@en
P2093
D H Perlmutter
H R Colten
P Kilbridge
T H Rossing
P2860
P304
P356
10.1073/PNAS.82.3.795
P407
P577
1985-02-01T00:00:00Z