Anti-virulence strategies to combat bacteria-mediated disease.
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The resveratrol tetramer (-)-hopeaphenol inhibits type III secretion in the gram-negative pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosaEffective--a database of predicted secreted bacterial proteinsNew Perspectives on the Use of Phytochemicals as an Emergent Strategy to Control Bacterial Infections Including BiofilmsThe arsenal of pathogens and antivirulence therapeutic strategies for disarming themAnti-biofilm Activity as a Health IssueThe effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulationBeyond killing: Can we find new ways to manage infection?Targeting Staphylococcus aureus Toxins: A Potential form of Anti-Virulence TherapySmall-Molecule Inhibitors of the Type III Secretion SystemVirulence and Fitness Determinants of Uropathogenic Escherichia coliCombating pathogenic microorganisms using plant-derived antimicrobials: a minireview of the mechanistic basisCollective sensing and collective responses in quorum-sensing bacteriaQuorum quenching revisited--from signal decays to signalling confusionFrom ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coliResistance to quorum-quenching compoundsProcessing the Interspecies Quorum-sensing Signal Autoinducer-2 (AI-2): CHARACTERIZATION OF PHOSPHO-(S)-4,5-DIHYDROXY-2,3-PENTANEDIONE ISOMERIZATION BY LsrG PROTEINSmall-molecule inhibitor binding to an N-acyl-homoserine lactone synthaseComparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct ClassesCrystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide LigandStructure of the Acinetobacter baumannii Dithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction SiteInsights into substrate binding and catalysis in bacterial type I dehydroquinaseApplication of fragment-based screening to the design of inhibitors of Escherichia coli DsbAThe Multifaceted Activity of the VirF Regulatory Protein in the Shigella LifestyleEmerging concepts promising new horizons for marine biodiscovery and synthetic biologyApigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysinNorlichexanthone Reduces Virulence Gene Expression and Biofilm Formation in Staphylococcus aureusHarbouring public good mutants within a pathogen population can increase both fitness and virulenceA comparison of computational methods for identifying virulence factorsChemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule productionOroxylin A inhibits hemolysis via hindering the self-assembly of α-hemolysin heptameric transmembrane porePartial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJSubtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosaSolonamide B inhibits quorum sensing and reduces Staphylococcus aureus mediated killing of human neutrophilsRational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activitySmall molecule deubiquitinase inhibitors promote macrophage anti-infective capacityIdentification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicityUnravelling the Structural and Molecular Basis Responsible for the Anti-Biofilm Activity of Zosteric AcidVirtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbAThe agr Inhibitors Solonamide B and Analogues Alter Immune Responses to Staphylococccus aureus but Do Not Exhibit Adverse Effects on Immune Cell FunctionsReconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.
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Anti-virulence strategies to combat bacteria-mediated disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Anti-virulence strategies to combat bacteria-mediated disease.
@en
Anti-virulence strategies to combat bacteria-mediated disease.
@nl
type
label
Anti-virulence strategies to combat bacteria-mediated disease.
@en
Anti-virulence strategies to combat bacteria-mediated disease.
@nl
prefLabel
Anti-virulence strategies to combat bacteria-mediated disease.
@en
Anti-virulence strategies to combat bacteria-mediated disease.
@nl
P356
P1476
Anti-virulence strategies to combat bacteria-mediated disease.
@en
P2093
David A Rasko
Vanessa Sperandio
P2888
P304
P356
10.1038/NRD3013
P577
2010-01-18T00:00:00Z