Novel RNA-based strategies for therapeutic gene silencing.
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Direct translocation as major cellular uptake for CADY self-assembling peptide-based nanoparticlesIdentification of allele-specific RNAi effectors targeting genetic forms of Parkinson's diseaseHypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA deliveryOligonucleotide-based strategies to combat polyglutamine diseases.Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexesMITF-siRNA formulation is a safe and effective therapy for human melasmaA simple and robust vector-based shRNA expression system used for RNA interference.Changes in innate and permissive immune responses after hbv transgenic mouse vaccination and long-term-siRNA treatment [corrected].Baculovirus-mediated miRNA regulation to suppress hepatocellular carcinoma tumorigenicity and metastasis.Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific.Single base mismatches in the mRNA target site allow specific seed region-mediated off-target binding of siRNA targeting human coagulation factor 7.Artificial mirtron-mediated gene knockdown: functional DMPK silencing in mammalian cellsSpecific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosisSilencing of Parkinson's disease-associated genes with artificial mirtron mimics of miR-1224.From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review).MicroRNAs as therapeutic targets in chemoresistance.Progress in microRNA delivery.Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing.microRNAs as a new mechanism regulating adipose tissue inflammation in obesity and as a novel therapeutic strategy in the metabolic syndrome.The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.MicroRNA replacement therapy for cancer.Mirtrons, an emerging class of atypical miRNA.The role of microRNAs in cardiovascular disease.Personalized gene silencing therapeutics for Huntington disease.The emerging role of miRNAs in inflammatory bowel disease: a review.microRNA-497 inhibits invasion and metastasis of colorectal cancer cells by targeting vascular endothelial growth factor-A.The effects of Livin shRNA on the response to cisplatin in HepG2 cells.microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2.Myeloid cells as orchestrators of the tumor microenvironment: novel targets for nanoparticular cancer therapy.MicroRNA-497 and bufalin act synergistically to inhibit colorectal cancer metastasis.Lentiviral small hairpin RNA delivery reduces apical sodium channel activity in differentiated human airway epithelial cells.Self-assembling peptide-based nanoparticles for siRNA delivery in primary cell lines.Development of hybrid baculovirus vectors for artificial MicroRNA delivery and prolonged gene suppression.Characterization of apoptosis and proliferation in esophageal carcinoma EC109 cells following siRNA-induced down-regulation of TRAF6.miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma.Dendronized gold nanoparticles for siRNA delivery.MicroRNAs as Molecular Targets for Cancer Therapy: On the Modulation of MicroRNA Expression.Functional VEGFA knockdown with artificial 3'-tailed mirtrons defined by 5' splice site and branch point.Glucan particles for selective delivery of siRNA to phagocytic cells in mice.
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Novel RNA-based strategies for therapeutic gene silencing.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 19 January 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Novel RNA-based strategies for therapeutic gene silencing.
@en
Novel RNA-based strategies for therapeutic gene silencing.
@nl
type
label
Novel RNA-based strategies for therapeutic gene silencing.
@en
Novel RNA-based strategies for therapeutic gene silencing.
@nl
prefLabel
Novel RNA-based strategies for therapeutic gene silencing.
@en
Novel RNA-based strategies for therapeutic gene silencing.
@nl
P2093
P2860
P356
P1433
P1476
Novel RNA-based strategies for therapeutic gene silencing.
@en
P2093
Christopher R Sibley
Matthew J A Wood
P2860
P304
P356
10.1038/MT.2009.306
P577
2010-01-19T00:00:00Z