Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators.
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Epithelial cell polarity: a major gatekeeper against cancer?Polarity in mammalian epithelial morphogenesisCellular foundations of mammary tubulogenesisDifferential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issuesPar6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.Epigenomic characterization of locally advanced anal cancer: a radiation therapy oncology group 98-11 specimen studyThe blood-testis barrier and its implications for male contraceptionInvolvement of Girdin in the determination of cell polarity during cell migrationPar6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesisRotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly.Control of MT1-MMP transport by atypical PKC during breast-cancer progression.Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cellsThe cell polarity protein Scrib functions as a tumor suppressor in liver cancer.Mutations in the polycomb group gene polyhomeotic lead to epithelial instability in both the ovary and wing imaginal disc in Drosophila.Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancerDynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesisNon-muscle myosins in tumor progression, cancer cell invasion, and metastasis.Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.Claudin 1 expression in basal-like breast cancer is related to patient ageOncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3.The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer.SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasiaTumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrityLoss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes.Snail destabilizes cell surface Crumbs3a.Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium.Epithelial Tumors Originate in Tumor Hotspots, a Tissue-Intrinsic Microenvironment.LIN7A is a major determinant of cell-polarity defects in breast carcinomasRiding the crest of the wave: parallels between the neural crest and cancer in epithelial-to-mesenchymal transition and migrationBreaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.Molecular mechanisms of tumor suppression by LKB1.The Hippo pathway and apico-basal cell polarity.Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors.Epithelial cell polarity, stem cells and cancer.Cell polarity as a regulator of cancer cell behavior plasticity.The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man.
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Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 21 January 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Polarity protein alterations i ...... roles for polarity regulators.
@en
Polarity protein alterations i ...... roles for polarity regulators.
@nl
type
label
Polarity protein alterations i ...... roles for polarity regulators.
@en
Polarity protein alterations i ...... roles for polarity regulators.
@nl
prefLabel
Polarity protein alterations i ...... roles for polarity regulators.
@en
Polarity protein alterations i ...... roles for polarity regulators.
@nl
P2860
P1476
Polarity protein alterations i ...... roles for polarity regulators.
@en
P2093
Ling Huang
Senthil K Muthuswamy
P2860
P356
10.1016/J.GDE.2009.12.001
P577
2010-01-21T00:00:00Z