A common genetic variant within SCN10A modulates cardiac SCN5A expression
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The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex InheritancePhysiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ComparisonInvestigating the transcriptional control of cardiovascular developmentDiscovery and validation of sub-threshold genome-wide association study loci using epigenomic signaturesGenetic networks governing heart development.Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data.Novel SCN10A variants associated with Brugada syndrome.Deleterious protein-altering mutations in the SCN10A voltage-gated sodium channel gene are associated with prolonged QT.52 Genetic Loci Influencing Myocardial Mass.Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1Pharmacology and Toxicology of Nav1.5-Class 1 anti-arrhythmic drugs.Genetics of Brugada syndrome.SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillationA novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cellsFunctional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesisRole of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced coughBrugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects.Common variation in atrial fibrillation: navigating the path from genetic association to mechanism.Novel Therapeutic Strategies for the Management of Ventricular Arrhythmias Associated with the Brugada SyndromeContrasting Nav1.8 Activity in Scn10a-/- Ventricular Myocytes and the Intact Heart.Neuronal Nav1.8 Channels as a Novel Therapeutic Target of Acute Atrial Fibrillation Prevention.Nav-igating through a complex landscape: SCN10A and cardiac conduction.Voltage-gated sodium channels in the mammalian heart.Genetics of congenital heart disease: the contribution of the noncoding regulatory genome.An update on risk factors for drug-induced arrhythmias.Spatiotemporal regulation of enhancers during cardiogenesis.TBX5: A Key Regulator of Heart Development.Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome.A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a.Development and Function of the Cardiac Conduction System in Health and Disease.A Missense Variant in PLEC Increases Risk of Atrial Fibrillation.Structure and function of the Nppa-Nppb cluster locus during heart development and disease.A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.[EXPRESS] A variant in the SCN10A enhancer may affect human mechanical pain sensitivity.RNA Binding Protein, HuR, Regulates SCN5A Expression Through Stabilizing MEF2C transcription factor mRNA.The Anatomy, Development, and Evolution of the Atrioventricular Conduction Axis
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A common genetic variant within SCN10A modulates cardiac SCN5A expression
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A common genetic variant within SCN10A modulates cardiac SCN5A expression
@en
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
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type
label
A common genetic variant within SCN10A modulates cardiac SCN5A expression
@en
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
@nl
prefLabel
A common genetic variant within SCN10A modulates cardiac SCN5A expression
@en
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
@nl
P2093
P2860
P50
P356
P1476
A common genetic variant within SCN10A modulates cardiac SCN5A expression
@en
P2093
Christine Seidman
Connie R Bezzina
David E Arnolds
David McKean
Ivan P Moskowitz
J G Seidman
Jochen D Muehlschlegel
Julia Moosmann
Malou van den Boogaard
Marcelo A Nobrega
P2860
P304
P356
10.1172/JCI73140
P407
P577
2014-03-18T00:00:00Z