A genome-wide association study of the human metabolome in a community-based cohort
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Alanine-glyoxylate aminotransferase 2 (AGXT2) polymorphisms have considerable impact on methylarginine and β-aminoisobutyrate metabolism in healthy volunteersGenetics of human metabolism: an updateGenome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levelsFrom Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized MedicineConsiderations when choosing a genetic model organism for metabolomics studiesMixing omics: combining genetics and metabolomics to study rheumatic diseases.Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.Severe child form of primary hyperoxaluria type 2 - a case report revealing consequence of GRHPR deficiency on metabolism.An atlas of genetic influences on human blood metabolites.Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster.PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.Analytical methods in untargeted metabolomics: state of the art in 2015.Metabolomics of renal venous plasma from individuals with unilateral renal artery stenosis and essential hypertensionDistinct metabolomic signatures are associated with longevity in humans.Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality.Dimethylglycine Deficiency and the Development of Diabetes.Gender-specific pathway differences in the human serum metabolome.Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.Mendelian randomization studies of biomarkers and type 2 diabetes.Choline metabolites: gene by diet interactions.A pilot, short-term dietary manipulation of branched chain amino acids has modest influence on fasting levels of branched chain amino acidsGenome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery diseaseMetabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program.An exome array study of the plasma metabolome.The structural origin of metabolic quantitative diversity.Plasma amino acid profiles in healthy East Asian subpopulations living in Japan.Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2Whole genome sequence analysis of serum amino acid levels.Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk.Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease.AGXT2: a promiscuous aminotransferase.The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities.Metabolomics and Metabolic Diseases: Where Do We Stand?Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1.Metabolomic Biomarkers in the Progression to Type 1 Diabetes.Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis.HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus.Short-term NO2 exposure is associated with long-chain fatty acids in prospective cohorts from Augsburg, Germany: results from an analysis of 138 metabolites and three exposures.A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study.
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A genome-wide association study of the human metabolome in a community-based cohort
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A genome-wide association study of the human metabolome in a community-based cohort
@en
A genome-wide association study of the human metabolome in a community-based cohort.
@nl
type
label
A genome-wide association study of the human metabolome in a community-based cohort
@en
A genome-wide association study of the human metabolome in a community-based cohort.
@nl
prefLabel
A genome-wide association study of the human metabolome in a community-based cohort
@en
A genome-wide association study of the human metabolome in a community-based cohort.
@nl
P2093
P2860
P50
P1433
P1476
A genome-wide association study of the human metabolome in a community-based cohort
@en
P2093
Amanda L Souza
Anahita Ghorbani
Christopher J O'Donnell
Clary Clish
Dongxiao Shen
Eugene P Rhee
Geoffrey A Walford
J-R Joanna Yeh
Jose C Florez
P2860
P304
P356
10.1016/J.CMET.2013.06.013
P577
2013-07-01T00:00:00Z