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No evidence of locus heterogeneity in familial microcephaly with or without chorioretinopathy, lymphedema, or mental retardation syndromeKinesin-5: cross-bridging mechanism to targeted clinical therapyKinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching.TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleIdentification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5Identification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cellsSeptin1 is required for spindle assembly and chromosome congression in mouse oocytesDynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2.PRC1 controls spindle polarization and recruitment of cytokinetic factors during monopolar cytokinesis.Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.Kinesin-12 differentially affects spindle assembly depending on its microtubule substrateKinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanismChromatids segregate without centrosomes during Caenorhabditis elegans mitosis in a Ran- and CLASP-dependent manner.Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.Kinesin-5 is a microtubule polymerase.Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward MetastasisRegulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics.Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast.Eg5 restricts anaphase B spindle elongation in mammalian cells.Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells.Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment.Transport by populations of fast and slow kinesins uncovers novel family-dependent motor characteristics important for in vivo function.Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization.The centrosome and its duplication cycleDynein Heavy Chain, Encoded by Two Genes in Agaricomycetes, Is Required for Nuclear Migration in Schizophyllum commune.Unconventional functions of microtubule motors.TPX2 regulates neuronal morphology through kinesin-5 interaction.Kinesin tail domains are intrinsically disordered.Phylogenetic analysis of the Kinesin superfamily from physcomitrellaDepletion of kinesin-12, a myosin-IIB-interacting protein, promotes migration of cortical astrocytesPTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis.Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.Loop L5 assumes three distinct orientations during the ATPase cycle of the mitotic kinesin Eg5: a transient and time-resolved fluorescence study.Optochemical control of RNA interference in mammalian cells.Mitotic motors and chromosome segregation: the mechanism of anaphase B.TPX2: of spindle assembly, DNA damage response, and cancer.Separate to operate: control of centrosome positioning and separation.The spindle assembly checkpoint promotes chromosome bi-orientation: A novel Mad1 role in chromosome alignment.The mechanics of microtubule networks in cell division.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitotic functions of kinesin-5.
@en
Mitotic functions of kinesin-5.
@nl
type
label
Mitotic functions of kinesin-5.
@en
Mitotic functions of kinesin-5.
@nl
prefLabel
Mitotic functions of kinesin-5.
@en
Mitotic functions of kinesin-5.
@nl
P2093
P2860
P1476
Mitotic functions of kinesin-5.
@en
P2093
Alyssa Gable
Nick P Ferenz
Pat Wadsworth
P2860
P304
P356
10.1016/J.SEMCDB.2010.01.019
P577
2010-01-28T00:00:00Z