SHP2 phosphatase as a novel therapeutic target for melanoma treatment. - Wikidata - awgldk - TriplyDB

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

http://www.wikidata.org/entity/Q37687479

about

Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma.Targeting Tyrosine Phosphatases: Time to End the Stigma.Therapeutic Targeting of Oncogenic Tyrosine Phosphatases.Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.Cytotoxic activity of Shp2 inhibitor fumosorinone in human cancer cells.Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition

P2860

Q37708971-3B5877C9-DB63-4268-8CF8-41032E553A6C Q39244433-0F2B1D2C-9584-4D27-BFE7-53C2452A60C7 Q47881716-27B840E2-E054-4887-80C3-754294487806 Q48103763-EAFED4C8-B7CE-4873-B704-A164A55E5AC2 Q55476455-CF5167F7-D386-489E-A44E-852096AC1CE0 Q57050402-902998B8-9EC8-4D5E-ADC7-C64BEB643B9B Q58097695-8581627A-46CF-4067-9F1E-7E4502834856

P2860

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

http://www.wikidata.org/entity/Q37687479

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 16 September 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@en

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@nl

type

label

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@en

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@nl

prefLabel

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@en

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@nl

P1433

Q37687479-BEB1A985-B4B4-49A6-8820-838572C39A50

P1476

Q37687479-367D8AC8-6D1D-40A3-9891-BD487B37A82B

P2093

Q37687479-0612A64D-A148-4390-9EFD-46DC85F0A896

Q37687479-0BE32F51-0357-4501-B5AF-4E6F92665592

Q37687479-30715ACC-9485-4456-8FA0-057E886336D3

Q37687479-4C826123-64CE-42BC-80E9-473964CE64F0

Q37687479-524CA448-C8F6-407D-95F2-5857E82163DB

Q37687479-5D51F394-1489-4C9F-82F6-0F88701D2902

Q37687479-6583346D-E797-4BE2-8DA6-09F4E71255F0

Q37687479-6D27A2EC-0BCE-4834-97AE-E31DAEB62DD0

Q37687479-F0E5E181-DF41-4AC8-85AA-9E9F8EE3AD50

P2860

Q37687479-01973428-B8D0-49AE-B00C-E087B3B12490

Q37687479-0C6DE631-7378-465F-8B9F-57068E7282C2

Q37687479-0D46FF4A-8785-48E1-9FBE-760EC070173C

Q37687479-2679A664-CB36-4143-BCC3-6C2821909BBB

Q37687479-2889D8D8-A954-47DB-BE8F-849EF5CF419C

Q37687479-292DB6E3-DA26-4191-AE59-9231CF544CBC

Q37687479-2FA258B4-08A4-41E2-A84A-605EEE432E7B

Q37687479-39FB8EBA-A76E-4475-B368-0E7067AD0CF9

Q37687479-3DCF9D59-213B-4BD1-BC2A-FAE99D593F86

Q37687479-3FB77038-A290-4DFC-9E74-ED580790774D

P304

Q37687479-9C056ED9-DE92-46A9-8B24-3E872F1CB5DC

P31

Q37687479-5CA84331-AD03-4DD9-BE87-1719EF493A54

P356

Q37687479-41BFA809-CFFA-4B63-9D61-155548119672

P407

Q37687479-25C041B1-6C6B-4DFE-BDC9-CA76BDA2CC05

P433

Q37687479-DA1D8C46-7583-408E-A1FB-BDE07169F5D7

P478

Q37687479-1F58DAA5-9EB4-43F5-9A1E-A541AD2ED907

P577

Q37687479-3FB28254-1280-4B10-A6AA-527261550C7A

P698

Q37687479-40874835-9190-4323-B5B9-BB3F81A97E74

P921

Q37687479-D7397087-0353-4004-A49B-B47EB14BEFE0

P932

Q37687479-5B34B578-01A1-4DF0-A517-8DA66DCD26A0

P356

ONCOTARGET.12074

P1433

P1476

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

@en

P2093

Jingwu Xie

http://www.w3.org/2001/XMLSchema#string

Jinmin Miao

http://www.w3.org/2001/XMLSchema#string

Lan Chen

http://www.w3.org/2001/XMLSchema#string

Lifan Zeng

http://www.w3.org/2001/XMLSchema#string

Ruo-Yu Zhang

http://www.w3.org/2001/XMLSchema#string

Sheng Zhang

http://www.w3.org/2001/XMLSchema#string

Yunpeng Bai

http://www.w3.org/2001/XMLSchema#string

Zhi-Hong Yu

http://www.w3.org/2001/XMLSchema#string

Zhong-Yin Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene

Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor

A landscape of driver mutations in melanoma

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo

P304

73817-73829

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.18632/ONCOTARGET.12074

http://www.w3.org/2001/XMLSchema#string

P407

P433

45

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2016-09-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27650545

http://www.w3.org/2001/XMLSchema#string

P921

P932

5342016

http://www.w3.org/2001/XMLSchema#string