Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.
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Signaling involved in stem cell reprogramming and differentiation.TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.
P2860
Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@en
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
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type
label
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@en
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@nl
prefLabel
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@en
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@nl
P2093
P2860
P356
P1476
Silencing of the EPHB3 tumor-s ...... of a transcriptional enhancer.
@en
P2093
Afsheen Yousaf
Amelie Proske
Hana Andrlová
Kerstin Rönsch
Marcel Jäger
Martin Werner
Miriam Bertrand
Monika Schrempp
Robert Zeiser
Sabine Jägle
P2860
P304
P356
10.1073/PNAS.1314523111
P407
P577
2014-03-18T00:00:00Z