Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.

Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.

Item
http://www.wikidata.org/entity/Q37688468
Ibrutinib, a Bruton's tyrosine kinase inhibitor, exhibits antitumoral activity and induces autophagy in glioblastoma.High expression of Bruton's tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma.Bruton's Tyrosine Kinase: An Emerging Key Player in Innate Immunity.Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins.Role of Bruton's tyrosine kinase in B cells and malignancies.Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α.Therapeutic Potential of Thymoquinone in Glioblastoma Treatment: Targeting Major Gliomagenesis Signaling Pathways.Novel Indications for Bruton's Tyrosine Kinase Inhibitors, beyond Hematological Malignancies.
P2860

Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.

Item
http://www.wikidata.org/entity/Q37688468
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 August 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Preclinical investigation of i ...... esis and stem cell phenotypes.
@en
Preclinical investigation of i ...... esis and stem cell phenotypes.
@nl
type
label
Preclinical investigation of i ...... esis and stem cell phenotypes.
@en
Preclinical investigation of i ...... esis and stem cell phenotypes.
@nl
prefLabel
Preclinical investigation of i ...... esis and stem cell phenotypes.
@en
Preclinical investigation of i ...... esis and stem cell phenotypes.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Preclinical investigation of i ...... nesis and stem cell phenotypes
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932