Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
about
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansBasal immunoglobulin signaling actively maintains developmental stage in immature B cells.B cells in chronic graft-versus-host diseaseImmunological aspects in chronic lymphocytic leukemia (CLL) developmentActin cytoskeletal defects in immunodeficiencyCD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1Receptor editing is the main mechanism of B cell tolerance toward membrane antigensThe motheaten mutation rescues B cell signaling and development in CD45-deficient micePhospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cellsThe src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytesShc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytesInhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseasesAge-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortalityRestricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms.Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry.Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.Why do B cell lymphoma fail to elicit clinically sufficient T cell immune responses?Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals.Environmentally induced autoimmune diseases: potential mechanismsScience, medicine, and the future: Tolerance and autoimmunityActivation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodiesReceptor selection in B and T lymphocytes.B cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.Immunobiology of allogeneic peripheral blood mononuclear cells mobilized with granulocyte-colony stimulating factor.Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigusMercury alters B-cell protein phosphorylation profiles.Immunosuppression without immunosuppression? How to be a tolerant individual in a dangerous world.Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph nodeExploring lymphocyte differentiation pathways.Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.The Ca2+-activated K+ channel of intermediate conductance:a possible target for immune suppression.Autoimmune and infectious skin diseases that target desmogleins.A B-cell receptor-specific selection step governs immature to mature B cell differentiationActivation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans.Isotype control of B cell signaling.Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling.Tolerance and autoimmunity in the eye: a role for CD8 T cells in organ-specific autoimmunity in the retina.A protective role for innate immunity in systemic lupus erythematosus.Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes.
P2860
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P2860
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@en
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@nl
type
label
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@en
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@nl
prefLabel
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@en
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@nl
P2860
P356
P1476
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires.
@en
P2093
Goodnow CC
P2860
P304
P356
10.1073/PNAS.93.6.2264
P407
P577
1996-03-01T00:00:00Z