Prognostic value and biological role of the kallikrein-related peptidases in human malignancies.
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Involvement of Kallikrein-Related Peptidases in Normal and Pathologic ProcessesEmerging clinical importance of the cancer biomarkers kallikrein-related peptidases (KLK) in female and male reproductive organ malignanciesGenetic association of the KLK4 locus with risk of prostate cancer.Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes.Genomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas.Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesionsClinical significance of human kallikrein 12 gene expression in gastric cancer.Knockdown of KLK11 inhibits cell proliferation and increases oxaliplatin sensitivity in human colorectal cancer.Targeting kallikrein-related peptidases in prostate cancer.Predictions for the future of kallikrein-related peptidases in molecular diagnostics.Potential nanotechnologies and molecular targets in the quest for efficient chemotherapy in ovarian cancer.Kallikrein-related peptidases targeted therapies in prostate cancer: perspectives and challenges.KLK4 silencing inhibits the growth of oral squamous cell carcinoma through Wnt/β-catenin signaling pathway.Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies.Significant alterations in the expression pattern of kallikrein-related peptidase genes KLK4, KLK5 and KLK14 after treatment of breast cancer cells with the chemotherapeutic agents epirubicin, docetaxel and methotrexate.Kallikrein-related peptidase 6 (KLK6)gene expression in intracranial tumors.Kallikrein-related peptidase 4 gene (KLK4) in prostate tumors: quantitative expression analysis and evaluation of its clinical significance.The kallikrein-related peptidase 13 (KLK13) gene is substantially up-regulated after exposure of gastric cancer cells to antineoplastic agents.Clinical relevance of the deregulated kallikrein-related peptidase 8 mRNA expression in breast cancer: a novel independent indicator of disease-free survival.Quantified KLK15 gene expression levels discriminate prostate cancer from benign tumors and constitute a novel independent predictor of disease progression.Multianalyte quantitative competitive PCR on optically encoded microspheres for an eight-gene panel related to prostate cancer.Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma.Downregulated KLK13 expression in bladder cancer highlights tumor aggressiveness and unfavorable patients' prognosis.Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell.Evaluation and prognostic significance of human tissue kallikrein-related peptidase 10 (KLK10) in colorectal cancerIdentification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer
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Prognostic value and biological role of the kallikrein-related peptidases in human malignancies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Prognostic value and biologica ...... tidases in human malignancies.
@en
Prognostic value and biologica ...... tidases in human malignancies.
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type
label
Prognostic value and biologica ...... tidases in human malignancies.
@en
Prognostic value and biologica ...... tidases in human malignancies.
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prefLabel
Prognostic value and biologica ...... tidases in human malignancies.
@en
Prognostic value and biologica ...... tidases in human malignancies.
@nl
P2860
P356
P1433
P1476
Prognostic value and biologica ...... tidases in human malignancies.
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P2860
P304
P356
10.2217/FON.09.149
P407
P577
2010-02-01T00:00:00Z