Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4.
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Production of leukotriene C4 in different human tissues is attributable to distinct membrane bound biosynthetic enzymesIdentification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthaseExpression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4Eosinophils in the 1990s: new perspectives on their role in health and diseaseThe organization and consequences of eicosanoid signalingThe Catalytic Architecture of Leukotriene C4 Synthase with Two Arginine ResiduesCysteinyl leukotrienes: multi-functional mediators in allergic rhinitisAccumulation of leukotriene C4 and histamine in human allergic skin reactionsGamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivoAsthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs.Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease.Activation of A3 adenosine receptors on human eosinophils elevates intracellular calciumPharmacotherapy of asthma in children, with special reference to leukotriene receptor antagonists.Leukotrienes in rhinitis.State of the art: therapeutic controversies in severe acute asthma.Fatty acids and atopic disease.Leukotriene A4 hydrolase in human bronchoalveolar lavage fluid.Navigating the sea of eicosanoids.Eosinophils altered phenotypically and primed by culture with granulocyte/macrophage colony-stimulating factor and 3T3 fibroblasts generate leukotriene C4 in response to FMLP.Endogenous leukotriene D4 formation during anaphylactic shock in the guinea pigUnraveling the complexity of lipid body organelles in human eosinophils.Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects.Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5.Pathophysiology of pruritus in atopic dermatitis: an overview.The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology.Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils."Helper" (CD4+) T cells and eosinophils in allergy and asthma.Effect of intravenous corticosteroid on ex vivo leukotriene generation by blood leucocytes of normal and asthmatic patients.Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae.Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor.Synergistic effects of LTB4 and LTD4 on leukocyte emigration into the guinea pig conjunctiva.Inhibitory effects of MK-886 on arachidonic acid metabolism in human phagocytesRole of inflammation in the hyperreactivity of the airways in asthmaMechanisms of eosinophil cytokine release.Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophagesDifferentiation in vitro of hybrid eosinophil/basophil granulocytes: autocrine function of an eosinophil developmental intermediate.Eosinophil lipid bodies: specific, inducible intracellular sites for enhanced eicosanoid formation.The potential effect of the extract of Crocus sativus and safranal on the total and differential white blood cells of ovalbumin-sensitized guinea pigsLipid droplets in leukocytes: Organelles linked to inflammatory responsestrans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation
P2860
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P2860
Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Generation and metabolism of 5 ...... production of leukotriene C4.
@en
Generation and metabolism of 5 ...... production of leukotriene C4.
@nl
type
label
Generation and metabolism of 5 ...... production of leukotriene C4.
@en
Generation and metabolism of 5 ...... production of leukotriene C4.
@nl
prefLabel
Generation and metabolism of 5 ...... production of leukotriene C4.
@en
Generation and metabolism of 5 ...... production of leukotriene C4.
@nl
P2093
P2860
P356
P1476
Generation and metabolism of 5 ...... production of leukotriene C4.
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.24.7626
P407
P577
1983-12-01T00:00:00Z