Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNAIFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIVIL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiationMast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation.Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptorTherapeutic efficacy of monthly subcutaneous injection of daclizumab in relapsing multiple sclerosisCyclosporin A inhibits CD40 ligand expression in T lymphocytes.Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.Interleukin-2 (IL-2) regulates the accessibility of the IL-2-responsive enhancer in the IL-2 receptor alpha gene to transcription factorsCD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammationDexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription.Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signaIncreased numbers of T lymphocytes with gamma delta-positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis.Defining a functionally distinct subset of human memory CD4+ T cells that are CD25POS and FOXP3NEG.Transcription of thrombomodulin mRNA in mouse hemangioma cells is increased by cycloheximide and thrombinSequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activationThe p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.GM-CSF and IL-2 as adjuvant enhance the immune effect of protein vaccine against foot-and-mouth disease.The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.Interleukin-2-dependent mechanisms of tolerance and immunity in vivoIL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients.GFP affects human T cell activation and cytokine production following in vitro stimulation.The role of soluble common gamma chain in autoimmune disease.Expression of thioredoxin in granulomas of sarcoidosis: possible role in the development of T lymphocyte activation.A DNA-binding activity, TRAC, specific for the TRA element of the transferrin receptor gene copurifies with the Ku autoantigenSequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytesFunctional role of HLA class I cell-surface molecules in human T-lymphocyte activation and proliferation.Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.Proliferative signals for suppressor T cells. Helper cells stimulated with pokeweed mitogen in vitro produce a suppressor cell growth factorAn IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein.Cell proliferation and expression of the transferrin receptor gene: promoter sequence homologies and protein interactions.Regulation of T cell autocrine growth. T4+ cells become refractory to interleukin 2.Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin AProduction of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsivenessInterleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene.Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling.
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Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
@en
type
label
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
@en
prefLabel
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
@en
P2093
P2860
P356
P1476
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
@en
P2093
P2860
P304
P356
10.1073/PNAS.82.12.4230
P407
P577
1985-06-01T00:00:00Z