Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.
about
Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulenceThe alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus.Mechanism of injury-provoked poliomyelitis.Complexes of poliovirus serotypes with their common cellular receptor, CD155unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNACis-acting RNA elements in human and animal plus-strand RNA virusesIntergeneric poliovirus recombinants for the treatment of malignant gliomaTherapeutic Use of Native and Recombinant EnterovirusesReplication-Competent Viruses as Cancer Immunotherapeutics: Emerging Clinical DataOncolytic virus therapy for glioblastoma multiforme: concepts and candidatesPoliovirus/Hepatitis C virus (internal ribosomal entry site-core) chimeric viruses: improved growth properties through modification of a proteolytic cleavage site and requirement for core RNA sequences but not for core-related polypeptides.The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation.A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element.Genetic analysis of a poliovirus/hepatitis C virus (HCV) chimera: interaction between the poliovirus cloverleaf and a sequence in the HCV 5' nontranslated region results in a replication phenotypeGenetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virusPoly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sitesTissue-Specific Replicating Capacity of a Chimeric Poliovirus That Carries the Internal Ribosome Entry Site of Hepatitis C Virus in a New Mouse Model Transgenic for the Human Poliovirus ReceptorInteraction of the poliovirus receptor with poliovirusTherapeutic and prevention strategies against human enterovirus 71 infectionDirect interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesisAbsence of internal ribosome entry site-mediated tissue specificity in the translation of a bicistronic transgeneGenetic changes found in a distinct clade of Enterovirus D68 associated with paralysis during the 2014 outbreak.Genetic recombination of poliovirus in a cell-free system.Genetic determinants of cell type-specific poliovirus propagation in HEK 293 cells.Recombinant oncolytic poliovirus eliminates glioma in vivo without genetic adaptation to a pathogenic phenotype.Evolution of the Sabin strain of type 3 poliovirus in an immunodeficient patient during the entire 637-day period of virus excretion.A predicted secondary structural domain within the internal ribosome entry site of echovirus 12 mediates a cell-type-specific block to viral replication.Translational control of viral gene expression in eukaryotesA nonpolio enterovirus with respiratory tropism causes poliomyelitis in intercellular adhesion molecule 1 transgenic mice.Cell-specific proteins regulate viral RNA translation and virus-induced diseasePreparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiformeHuman enterovirus 109: a novel interspecies recombinant enterovirus isolated from a case of acute pediatric respiratory illness in Nicaragua.Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulencePoliovirus tropism and attenuation are determined after internal ribosome entryOncolytic viruses as therapeutic agents.MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirusGenetically stable picornavirus expression vectors with recombinant internal ribosomal entry sitesActivity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region.Oncolytic polio virotherapy of cancerAge-dependent poliovirus replication in the mouse central nervous system is determined by internal ribosome entry site-mediated translation.
P2860
Q24516964-9D67A471-6C4F-4481-B94E-992E147BC488Q24519073-0E78CB94-E451-4034-9FD8-7ECA94314FF3Q24523568-8BEC529F-651E-4DD4-8F54-B84232F95FBCQ24554469-C6BBF487-67CF-4C8B-A358-B19DDDCD311EQ24608002-32015FD7-3F28-4A54-8E80-1E6EFB6FEECEQ24649975-7529C027-8BF4-4B4C-8CCA-308F750ED99AQ24682902-550B2AFB-3F32-4133-80C3-6DC32BBEEAF1Q26767082-9B38B946-2AA6-47AE-BB4A-A3C7F12D1FF0Q26801501-9A95E801-1CDF-497B-A4C3-5326271D1B93Q27007519-7E4B0079-A12E-47E7-8F68-E63FEC350E78Q27469345-AE2BCF5B-8B25-478A-BCF8-CBE8E7DD6858Q27469504-422C2F7F-B408-4EEC-BC69-628A887118FAQ27469576-BDD30B6B-F8FC-4118-93B7-191D48E996DCQ27469671-5E4E7AA3-85D9-4BC5-8AF4-C3183B23F87CQ27469901-3C0701DA-604C-468A-A16B-4C1E0ADCDD50Q27480995-E8AFFE47-6E89-4F9F-8A9B-D5F705DE9D2CQ27485662-5FBA5A0A-3E9F-444D-ACAC-32D45253CE15Q27620834-11330E33-5C2F-4ED8-BEFB-F127CA914516Q28080796-E542E909-C54A-46DD-8259-9344168469CDQ28475329-5CD0EAD8-566D-47F6-A744-F42D5651DE62Q33643156-F3764B4E-0EB2-4EEA-B931-4E4BE4191CB1Q33660302-5234149B-64FD-4070-9858-C60544DD2C0BQ33727277-D0BC69BF-53FB-4F79-93AA-9E5C4CA86B86Q33780697-CF84CC54-5812-49DA-B54F-D12BC2DA08E9Q33797119-78FC39FF-5748-4326-9872-6D46848CB74DQ33800863-2EBBE3C7-BC42-4491-BAE5-8B743FA6FCEAQ33843227-6651074B-DBC6-4FC1-A61B-285203BB8B06Q33935121-75CD690D-2FBC-41CA-911F-F1B7A7840FB0Q33981201-E324DAF7-46BC-43C9-9E21-5BE147DE4077Q34084984-A763B8AD-DF3F-4660-ADE4-46C984B0AF5DQ34105106-E26605C0-6F86-4664-947F-C59F06785ED6Q34120098-900BF66C-51EA-4321-BD1D-34A100678CA5Q34124035-3244AD80-E50E-43DC-9ADE-A3C54D8021B2Q34327208-957CC1E3-AF28-4C57-A3C4-CFD86C5634F9Q34329548-031A1E37-0648-44F4-B06E-ACB975A5D83DQ34343725-FACF133E-D383-4163-BA9D-15ECD8972E06Q34361592-5C6AC824-F03D-405C-8827-60BE5ABFDC80Q34391227-D7F7FA1C-972B-4F46-8E9E-02E3CD77E18BQ34425385-E806456E-4A28-45E7-BF91-D92360099F97Q34434880-CBE9ECC1-363C-4C05-AAFF-CB7C853F49D9
P2860
Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Internal ribosomal entry site ...... neric poliovirus recombinants.
@en
Internal ribosomal entry site ...... neric poliovirus recombinants.
@nl
type
label
Internal ribosomal entry site ...... neric poliovirus recombinants.
@en
Internal ribosomal entry site ...... neric poliovirus recombinants.
@nl
prefLabel
Internal ribosomal entry site ...... neric poliovirus recombinants.
@en
Internal ribosomal entry site ...... neric poliovirus recombinants.
@nl
P2093
P2860
P356
P1476
Internal ribosomal entry site ...... neric poliovirus recombinants.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.6.2370
P407
P577
1996-03-01T00:00:00Z