mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
about
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesisIdentification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.Identification and development of mPGES-1 inhibitors: where we are at?PGE2 signaling and its biosynthesis-related enzymes in cholangiocarcinoma progression.Role of COX-2/mPGES-1/prostaglandin E2 cascade in kidney injury.Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.Non-cell autonomous effects of targeting inducible PGE2 synthesis during inflammation-associated colon carcinogenesisDiscovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol.Prostaglandins in cancer cell adhesion, migration, and invasionStructure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.Anti-tumor enhancement of Fei-Liu-Ping ointment in combination with celecoxib via cyclooxygenase-2-mediated lung metastatic inflammatory microenvironment in Lewis lung carcinoma xenograft mouse modelMechanistic aspects of COX-2 expression in colorectal neoplasiaNon-steroid anti-inflammatory drugs, prostaglandins, and cancer.Prostaglandin E2 EP receptors as therapeutic targets in breast cancer.Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancerGenetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.In Vitro Protective Effects of Lycium barbarum Berries Cultivated in Umbria (Italy) on Human Hepatocellular Carcinoma Cells.Characterization of microsomal prostaglandin E synthase 1 inhibitors.Aspirin and colorectal cancer: the promise of precision chemoprevention.Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E2 Synthase 1 and Ser127 Is NotStructural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma.Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice.Arzanol, a potent mPGES-1 inhibitor: novel anti-inflammatory agent.Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway.
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P2860
mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 February 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@en
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@nl
type
label
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@en
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@nl
prefLabel
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@en
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@nl
P2093
P2860
P1433
P1476
mPGES-1 as a target for cancer ...... ipase A2 and lipid mediators".
@en
P2093
Daniel W Rosenberg
Emmanuelle J Meuillet
Masako Nakanishi
Vijay Gokhale
P2860
P304
P356
10.1016/J.BIOCHI.2010.02.006
P577
2010-02-13T00:00:00Z