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Modelling and simulation as research tools in paediatric drug developmentConsiderations for a Pediatric Biopharmaceutics Classification System (BCS): application to five drugs.Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomicsPeak cortisol response to corticotropin-releasing hormone is associated with age and body size in children referred for clinical testing: a retrospective review.Scaling of pharmacokinetics across paediatric populations: the lack of interpolative power of allometric models.Variation in prescribing patterns and therapeutic drug monitoring of intravenous busulfan in pediatric hematopoietic cell transplant recipientsChallenges and considerations for development of therapeutic proteins in pediatric patients.Modeling and simulation in pediatric drug therapy: Application of pharmacometrics to define the right dose for children.Optimizing treatment outcome of first-line anti-tuberculosis drugs: the role of therapeutic drug monitoring.Bottom-up Meets Top-down: Complementary Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling for Regulatory Approval of a Dosing Algorithm of Valganciclovir in Very Young Children.Regulatory experience with physiologically based pharmacokinetic modeling for pediatric drug trials.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Pediatric dose selection.
@en
Pediatric dose selection.
@nl
type
label
Pediatric dose selection.
@en
Pediatric dose selection.
@nl
prefLabel
Pediatric dose selection.
@en
Pediatric dose selection.
@nl
P2860
P356
P1476
Pediatric dose selection.
@en
P2093
D R Abernethy
G J Burckart
P2860
P304
P356
10.1038/CLPT.2009.292
P407
P577
2010-03-01T00:00:00Z