Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome
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ATRX directs binding of PRC2 to Xist RNA and Polycomb targetsEpigenetic predisposition to expression of TIMP1 from the human inactive X chromosome.X chromosome inactivation and active X upregulation in therian mammals: facts, questions, and hypothesesEvolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammalsImmunostaining of modified histones defines high-level features of the human metaphase epigenomeX chromosome inactivation and Xist evolution in a rodent lacking LINE-1 activityHistone variants and epigenetics.The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequencesLoss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression.Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci.The evolution of the histone methyltransferase gene Su(var)3-9 in metazoans includes a fusion with and a re-fission from a functionally unrelated geneEvidence of influence of genomic DNA sequence on human X chromosome inactivationThe impact of local genome sequence on defining heterochromatin domains.Domain-wide regulation of DNA replication timing during mammalian developmentSpread of X-chromosome inactivation into autosomal sequences: role for DNA elements, chromatin features and chromosomal domainsActive and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation.Variable escape from X-chromosome inactivation: identifying factors that tip the scales towards expressionEpigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation.Nuclear organization and dosage compensation.Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.Evidence for sequence biases associated with patterns of histone methylation.X-chromosome inactivation: a hypothesis linking ontogeny and phylogeny.Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome.The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and γ-H2AXChromosome organization and chromatin modification: influence on genome function and evolution.Histone modification patterns associated with the human X chromosomeCathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.Variation in array size, monomer composition and expression of the macrosatellite DXZ4Dynamics of the two heterochromatin types during imprinted X chromosome inactivation in vole Microtus levis.Xist regulation and function explored.Evolutionary diversity and developmental regulation of X-chromosome inactivation.A deletion at the mouse Xist gene exposes trans-effects that alter the heterochromatin of the inactive X chromosome and the replication time and DNA stability of both X chromosomes.Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin.The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity.Allele-specific distribution of RNA polymerase II on female X chromosomesEpigenetic control of embryonic renal cell differentiation by L1 retrotransposon.The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancerDiverse factors are involved in maintaining X chromosome inactivationCharacterization of DXZ4 conservation in primates implies important functional roles for CTCF binding, array expression and tandem repeat organization on the X chromosome.
P2860
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P2860
Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Multiple spatially distinct ty ...... he human inactive X chromosome
@en
Multiple spatially distinct ty ...... e human inactive X chromosome.
@nl
type
label
Multiple spatially distinct ty ...... he human inactive X chromosome
@en
Multiple spatially distinct ty ...... e human inactive X chromosome.
@nl
prefLabel
Multiple spatially distinct ty ...... he human inactive X chromosome
@en
Multiple spatially distinct ty ...... e human inactive X chromosome.
@nl
P2860
P356
P1476
Multiple spatially distinct ty ...... he human inactive X chromosome
@en
P2093
Brian P Chadwick
Huntington F Willard
P2860
P304
17450-17455
P356
10.1073/PNAS.0408021101
P407
P577
2004-12-01T00:00:00Z