Coumarins: old compounds with novel promising therapeutic perspectives.
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Sparstolonin B, a novel plant derived compound, arrests cell cycle and induces apoptosis in N-myc amplified and N-myc nonamplified neuroblastoma cellsBright building blocks for chemical biologyNovel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells.Anti-inflammatory properties of extracts from Chimonanthus nitens Oliv. leaf.Analysis of flavonoids by graphene-based surface-assisted laser desorption/ionization time-of-flight mass spectrometry.Evaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative DNA damage in human lymphocytesInduction of Nur77-dependent apoptotic pathway by a coumarin derivative through activation of JNK and p38 MAPKA prodrug approach to the use of coumarins as potential therapeutics for superficial mycoses.Resveratrol and Coumarin: Novel Agricultural Antibacterial Agent against Ralstonia solanacearum In Vitro and In Vivo.Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.Synthesis and evaluation of anticancer activity of 6-pyrazolinylcoumarin derivatives.In silico genotoxicity of coumarins: application of the Phenol-Explorer food database to functional food science.Synthesis and cytotoxic activities of novel 4-methoxy-substituted and 5-methyl-substituted (3'S,4'S)-(-)-cis-khellactone derivatives that induce apoptosis via the intrinsic pathway.Synthesis, Fluorescence Properties, and Antiproliferative Potential of Several 3-Oxo-3H-benzo[f]chromene-2-carboxylic Acid Derivatives.Uses of 3-(2-Bromoacetyl)-2H-chromen-2-one in the Synthesis of Heterocyclic Compounds Incorporating Coumarin: Synthesis, Characterization and Cytotoxicity.Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth.Anti-tumour activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.The cytotoxic activities of 7-isopentenyloxycoumarin on 5637 cells via induction of apoptosis and cell cycle arrest in G2/M stage.Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives.Molecular interplay between cdk4 and p21 dictates G0/G1 cell cycle arrest in prostate cancer cellsPropofol-induced protection of SH-SY5Y cells against hydrogen peroxide is associated with the HO-1 via the ERK pathway.In situ screening of 3-arylcoumarin derivatives reveals new inhibitors of mast cell degranulation.A facile transformation of amino acids to functionalized coumarins.Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors.Synthesis and pharmacological evaluations of 4-hydroxycoumarin derivatives as a new class of anti-Staphylococcus aureus agents.Mutation at G103 of MtbFtsZ Altered their Sensitivity to CoumarinsCoumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications.Phytochemicals as inhibitors of bacterial cell division protein FtsZ: coumarins are promising candidates.Diversity-oriented general protocol for the synthesis of privileged oxygen scaffolds: pyrones, coumarins, benzocoumarins and naphthocoumarins.Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites.Umbelliferone and esculetin protect against N-nitrosodiethylamine-induced hepatotoxicity in rats.Microwave-assisted synthesis and antitumor evaluation of a new series of thiazolylcoumarin derivatives.Synthesis, antitumor activity evaluation, and DNA-binding study of coumarin-based agents.Coumarin-appended phosphorescent cyclometalated iridium(iii) complexes as mitochondria-targeted theranostic anticancer agents.In vivo growth inhibition of sarcoma 180 by Kielmeyera rugosa Choisy (Calophyllaceae).An efficient approach toward formation of polycyclic coumarin derivatives via carbocation-initiated [4+2] cycloaddition and atom-economical photo-irradiated cyclization.Microwave-assisted Synthesis and antifungal activity of coumarin[8,7-e][1,3]oxazine derivatives.Structural elucidation of a series of 6-methyl-3-carboxamidocoumarins.Anti-Neuroinflammatory Effect of MC13, a Novel Coumarin Compound From Condiment Murraya, Through Inhibiting Lipopolysaccharide-Induced TRAF6-TAK1-NF-κB, P38/ERK MAPKS and Jak2-Stat1/Stat3 Pathways.Exploring coumarin potentialities: development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold
P2860
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P2860
Coumarins: old compounds with novel promising therapeutic perspectives.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Coumarins: old compounds with novel promising therapeutic perspectives.
@en
Coumarins: old compounds with novel promising therapeutic perspectives.
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type
label
Coumarins: old compounds with novel promising therapeutic perspectives.
@en
Coumarins: old compounds with novel promising therapeutic perspectives.
@nl
prefLabel
Coumarins: old compounds with novel promising therapeutic perspectives.
@en
Coumarins: old compounds with novel promising therapeutic perspectives.
@nl
P2093
P1476
Coumarins: old compounds with novel promising therapeutic perspectives.
@en
P2093
De Kimpe N
Moglioni A
Riveiro ME
P304
P356
10.2174/092986710790936284
P577
2010-01-01T00:00:00Z