Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models. - Wikidata - awgldk - TriplyDB

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

http://www.wikidata.org/entity/Q37696004

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Glucocerebrosidase expression patterns in the non-human primate brain.Lipid Involvement in Neurodegenerative Diseases of the Motor System: Insights from Lysosomal Storage Diseases.Autophagy impairment in Parkinson's disease.Molecular mechanisms of α-synuclein and GBA1 in Parkinson's disease.Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease.Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain.Is Parkinson's disease a lysosomal disorder?α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies

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Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

http://www.wikidata.org/entity/Q37696004

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 21 February 2017

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@en

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@nl

type

label

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@en

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@nl

prefLabel

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@en

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@nl

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PNAS.1616152114

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

@en

P2093

Amy M Richards

http://www.w3.org/2001/XMLSchema#string

Bing Wang

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Catherine Viel

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Christopher M Treleaven

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Elina Makino

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Hyejung Park

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James C Dodge

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Jennifer Clarke

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John Marshall

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Lamya S Shihabuddin

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P2860

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

Systemic delivery of a glucosylceramide synthase inhibitor reduces CNS substrates and increases lifespan in a mouse model of type 2 Gaucher disease

Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

Molecular pathways of neurodegeneration in Parkinson's disease

Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease.

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2699-2704

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scholarly article

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10.1073/PNAS.1616152114

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10

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114

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2017-02-21T00:00:00Z

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5347608

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