Targeting notch signaling pathway in cancer: clinical development advances and challenges
about
Export of microRNAs: A Bridge between Breast Carcinoma and Their Neighboring CellsAnti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical AppraisalSignaling Pathways in Thyroid Cancer and Their Therapeutic ImplicationsHPV-p53-miR-34a axis in HPV-associated cancersNovel therapies in small cell lung cancerTherapies targeting cancer stem cells: Current trends and future challengesNotch signaling deregulation in multiple myeloma: A rational molecular targetNrf2 and Notch Signaling in Lung Cancer: Near the CrossroadThe Eighth Central European Conference "Chemistry towards Biology": SnapshotAdipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity.Oncogenic role of Merlin/NF2 in glioblastoma.The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targetsA unified model of the hierarchical and stochastic theories of gastric cancer.Inhibition of notch signaling in combination with Paclitaxel reduces platinum-resistant ovarian tumor growth.Targeting Notch Signaling in Colorectal Cancer.Notch signaling in serous ovarian cancer.PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application.New, tolerable γ-secretase inhibitor takes desmoid down a notch.Developmental exposure to 2,3,7,8 tetrachlorodibenzo-p-dioxin attenuates later-life Notch1-mediated T cell development and leukemogenesis.Notch1 phenotype and clinical stage progression in non-small cell lung cancerGenome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells.Notch suppresses angiogenesis and progression of hepatic metastasesThe role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy.The NOTCH signaling pathway in normal and malignant blood cell production.Involvement of Notch1/Hes signaling pathway in ankylosing spondylitis.Notch1 downregulation combined with interleukin-24 inhibits invasion and migration of hepatocellular carcinoma cells.Small cell lung cancer: will recent progress lead to improved outcomes?Gamma secretase inhibitor enhances sensitivity to doxorubicin in MDA-MB-231 cells.Role of hypoxia-related proteins in invasion of ameloblastoma cells: crosstalk between NOTCH1, hypoxia-inducible factor 1α, a disintegrin and metalloproteinase 12, and heparin-binding epidermal growth factor.Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical updateA 10-gene expression signature of Notch pathway predicts recurrence in ovarian carcinomaThe Therapeutic Challenge of Targeting HER2 in Endometrial CancerDisrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain InhibitionNotch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL.Hes1: a key role in stemness, metastasis and multidrug resistance.Ethanol inhibits γ-secretase proteolytic activity in vascular smooth muscle cells.Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemiaPS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway.Synchronized Targeting of Notch and ERBB Signaling Suppresses Melanoma Tumor Growth through Inhibition of Notch1 and ERBB3.
P2860
Q26744487-4987346E-DF20-4580-985E-D4EE25635BB5Q26744536-37EFDE2F-B797-488C-A5B1-ABF35DD42A14Q26764899-B82B0FD8-2A67-492A-9111-93A78D62A1BCQ26770487-D32C62BB-27F6-400B-8521-93A19749F8EEQ26775390-054FB547-1ED9-4EE7-A935-A16F571EB803Q26777880-04D8FE07-5B5F-42CB-A779-683C223BED6BQ26797283-E5135F00-9957-4341-9789-7AF4324033D8Q28066915-DB46D733-C3C1-42EA-906E-1977E988419AQ28817788-EC984E61-D4A8-4D43-8557-4951354674A2Q30384852-CD41895C-B4D4-4A09-8B14-29E724B68937Q30398838-78E10BC1-96B7-4941-80BD-0074A1FA4D3DQ33566723-C017DE95-72C1-40DD-BC01-6DA6B4B7DC33Q33577624-868151F8-072E-4048-80AA-1E79B4E7692DQ33851035-6B86C6E4-0043-4DA2-AF99-B266B8D4CF63Q34482399-ED8BA4A1-EC54-4865-9463-4A0D870AF0DCQ34491211-4B438C0B-AD39-411D-8551-1FF2E721CE16Q34535041-66B9D489-D0B4-46A1-BE6A-7FAEBA430BB5Q34712645-DEACDAEF-AC54-4964-AE86-BE0F8B1501A4Q35013808-A4CED5A2-C2E9-4B78-82D3-378B5B5C3233Q35090915-6621DC52-2626-416E-BBD0-F0BF7190DD98Q35129205-89AAAC0F-714E-44F2-AE6B-35432060EF13Q35416653-D3D67C8E-D7E3-4AA8-AC0A-DED0858A06CDQ35463593-C7B1C256-E473-485B-80C0-ADCBB1901ADDQ35524598-3052BCBE-F4E5-4B6B-AC8E-ED50EC6B96F1Q35554465-04179E42-3BB4-4089-B530-6673C9289DD4Q35632152-30D94A05-CE51-4352-8C59-3883A5CCE4B3Q35771063-3A88D295-FA45-4971-848A-AD7F4EA1F66DQ35836257-B46B80E6-7A9C-4872-8F68-FFC2B0C53013Q35853842-9BB703C2-C6CB-42F9-8484-4491E4949A78Q35879045-8190BE1B-B9AB-464C-A1E7-74A5543D4DD6Q35904534-CEE8D5E7-834E-4669-B597-BE208FABE866Q35944512-7192F475-D3FC-4357-9C1C-B1EDB6798F22Q36064912-B99C8C4C-A5F7-4130-A8CE-7F88C28BCCAFQ36130555-984316F2-56FD-4D45-A93A-15225F8FA22AQ36140862-8C06DD34-6221-46E8-A0E0-B5DCB187DF69Q36213706-3BC19A53-F99B-4C34-B262-4A18D1C92162Q36219884-5EBCE7CE-C6BB-487F-B036-91AC951767EDQ36376809-B846600F-1D9F-4D42-BF1C-7FCA114E5D7DQ36621295-BC668AED-2F2E-412E-B685-F6199B03B61BQ36682137-890721C0-F960-4CFD-9229-8FB997B3B0C8
P2860
Targeting notch signaling pathway in cancer: clinical development advances and challenges
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting notch signaling pathway in cancer: clinical development advances and challenges
@en
Targeting notch signaling path ...... pment advances and challenges.
@nl
type
label
Targeting notch signaling pathway in cancer: clinical development advances and challenges
@en
Targeting notch signaling path ...... pment advances and challenges.
@nl
prefLabel
Targeting notch signaling pathway in cancer: clinical development advances and challenges
@en
Targeting notch signaling path ...... pment advances and challenges.
@nl
P2093
P2860
P1476
Targeting notch signaling pathway in cancer: clinical development advances and challenges
@en
P2093
Dat Nguyen
Naoko Takebe
Sherry X Yang
P2860
P304
P356
10.1016/J.PHARMTHERA.2013.09.005
P577
2013-09-27T00:00:00Z