Functional heterogeneity of genetically defined subclones in acute myeloid leukemia - Wikidata - awgldk - TriplyDB

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

http://www.wikidata.org/entity/Q37698123

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Humanized hemato-lymphoid system mice The influence of subclonal resistance mutations on targeted cancer therapy Translational implications of tumor heterogeneity Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging Advancing the Minimal Residual Disease Concept in Acute Myeloid Leukemia Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin Measurable residual disease testing in acute myeloid leukaemia.Current Management of Childhood Acute Myeloid Leukemia.Translating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity.Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia.Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes.The AML salad bowl.Current status and perspectives of patient-derived xenograft models in cancer research.Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.Clonal evolution in myelodysplastic syndromes Tracing dynamics and clonal heterogeneity of Cbx7-induced leukemic stem cells by cellular barcoding.Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.Cytogenetic heterogeneity negatively impacts outcomes in patients with acute myeloid leukemia.Cancer stem cells as a target population for drug discovery.Optimizing cancer genome sequencing and analysis.Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells.High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy.Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue.Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche.Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene?Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment.Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

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Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

http://www.wikidata.org/entity/Q37698123

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 06 March 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

@en

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

@nl

type

label

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

@en

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

@nl

prefLabel

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

@en

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

@nl

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J.CCR.2014.01.031

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Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

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Christopher A Miller

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Daniel C Link

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David H Spencer

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Elaine R Mardis

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Jeffery M Klco

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John F Dipersio

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Matthew J Walter

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Michelle O'Laughlin

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Richard K Wilson

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Robert S Fulton

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P2860

Intratumor heterogeneity: evolution through space and time

Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts

Recurring mutations found by sequencing an acute myeloid leukemia genome

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

DNMT3A Mutations in Acute Myeloid Leukemia

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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scholarly article

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10.1016/J.CCR.2014.01.031

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3

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Malachi Griffith

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2014-03-06T00:00:00Z

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260682120

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