Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies.
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Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolveTherapeutic Targeting of AutophagyNano-antacids enhance pH neutralization beyond their bulk counterparts: synthesis and characterization.20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicinRNA interference targeting CD147 inhibits the proliferation, invasiveness, and metastatic activity of thyroid carcinoma cells by down-regulating glycolysis.Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer.AGPAT9 suppresses cell growth, invasion and metastasis by counteracting acidic tumor microenvironment through KLF4/LASS2/V-ATPase signaling pathway in breast cancerSignificantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicinClinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects.Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular CarcinomaEfficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells.Research progress of hydroxychloroquine and autophagy inhibitors on cancer.The acidic microenvironment as a possible niche of dormant tumor cells.Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors.Glucose Restriction Combined with Autophagy Inhibition and Chemotherapy in HCT 116 Spheroids Decreases Cell Clonogenicity and Viability Regulated by Tumor Suppressor Genes.Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cellsStudy of the influence of the ph of water in the initiation of digestive tract injury in cadmium poisoning in rats.Targeting autophagy in cancer.A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation.Monocarboxylate Transporter-1 Mediates the Protective Effects of Neutral-pH Bicarbonate/Lactate-Buffered Peritoneal Dialysis Fluid on Cell Viability and Apoptosis.Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity.Radio frequency triggered curcumin delivery from thermo and pH responsive nanoparticles containing gold nanoparticles and its in vivo localization studies in an orthotopic breast tumor modelNanodiamond autophagy inhibitor allosterically improves the arsenical-based therapy of solid tumorsA drug screening assay on cancer cells chronically adapted to acidosisInhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis
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P2860
Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies.
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article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 31 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Acidic extracellular pH neutra ...... ications for cancer therapies.
@en
Acidic extracellular pH neutra ...... ications for cancer therapies.
@nl
type
label
Acidic extracellular pH neutra ...... ications for cancer therapies.
@en
Acidic extracellular pH neutra ...... ications for cancer therapies.
@nl
prefLabel
Acidic extracellular pH neutra ...... ications for cancer therapies.
@en
Acidic extracellular pH neutra ...... ications for cancer therapies.
@nl
P2093
P2860
P356
P1433
P1476
Acidic extracellular pH neutra ...... lications for cancer therapies
@en
P2093
Angela Strambi
Chiara Zipoli
Maria Hägg-Olofsson
Paola Pellegrini
Stig Linder
P2860
P304
P356
10.4161/AUTO.27901
P577
2014-01-31T00:00:00Z