Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.
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Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients.High Frequency of Genetic Recombination Is a Common Feature of Primate Lentivirus ReplicationIdentification of a minimal region of the HIV-1 5'-leader required for RNA dimerization, NC binding, and packagingStructural determinants and mechanism of HIV-1 genome packagingRole of the DIS hairpin in replication of human immunodeficiency virus type 1Evidence for preferential copackaging of Moloney murine leukemia virus genomic RNAs transcribed in the same chromosomal siteIs HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?A new NMR solution structure of the SL1 HIV-1Lai loop-loop dimerViral quasispecies evolutionHIV-1 reverse transcription5-Azacytidine and RNA secondary structure increase the retrovirus mutation rateDimer initiation sequence of HIV-1Lai genomic RNA: NMR solution structure of the extended duplexCross- and Co-Packaging of Retroviral RNAs and Their ConsequencesNMR Studies of the Structure and Function of the HIV-1 5'-LeaderIdentification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitroThe antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rateAccurately measuring recombination between closely related HIV-1 genomesProbing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analysesLower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseMolecular Epidemiology of Human Immunodeficiency Virus.Long-range recombination gradient between HIV-1 subtypes B and C variants caused by sequence differences in the dimerization initiation signal region.The role of recombination in the emergence of a complex and dynamic HIV epidemic.Genomic Diversity of Human Immunodeficiency Viruses.RNA structures facilitate recombination-mediated gene swapping in HIV-1Full-length sequence and mosaic structure of a human immunodeficiency virus type 1 isolate from ThailandInfectious molecular clones with the nonhomologous dimer initiation sequences found in different subtypes of human immunodeficiency virus type 1 can recombine and initiate a spreading infection in vitro.Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factorInfluence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutant frequencies.3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.Multiploid inheritance of HIV-1 during cell-to-cell infection.Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleteriousInfluence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors.Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses.In vivo rescue of a silent tax-deficient bovine leukemia virus from a tumor-derived ovine B-cell line by recombination with a retrovirally transduced wild-type tax gene.Drastic fitness loss in human immunodeficiency virus type 1 upon serial bottleneck events.Host-specific modulation of the selective constraints driving human immunodeficiency virus type 1 env gene evolution.Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, KenyaMolecular epidemiology of feline immunodeficiency virus in the domestic cat (Felis catus).Lentiviral vectors can be used for full-length dystrophin gene therapyGenetic recombination of human immunodeficiency virus type 1 in one round of viral replication: effects of genetic distance, target cells, accessory genes, and lack of high negative interference in crossover events
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P2860
Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genetic consequences of packag ...... rate of genetic recombination.
@en
Genetic consequences of packag ...... rate of genetic recombination.
@nl
type
label
Genetic consequences of packag ...... rate of genetic recombination.
@en
Genetic consequences of packag ...... rate of genetic recombination.
@nl
prefLabel
Genetic consequences of packag ...... rate of genetic recombination.
@en
Genetic consequences of packag ...... rate of genetic recombination.
@nl
P2860
P356
P1476
Genetic consequences of packag ...... rate of genetic recombination.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.4.1556
P407
P577
1990-02-01T00:00:00Z