T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
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mTOR Regulation of Lymphoid Cells in Immunity to PathogensSignaling in T cells - is anything the m(a)TOR with the picture(s)?Metabolic regulation of T cell differentiation and functionT cell metabolism drives immunityIntegrating canonical and metabolic signalling programmes in the regulation of T cell responsesTsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programsGene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte developmentFAM65B controls the proliferation of transformed and primary T cells.Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease.Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infectionsInsight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.Metabolic control of regulatory T cell development and function.mTOR signaling, Tregs and immune modulation.Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.mTOR Links Environmental Signals to T Cell Fate Decisions.mTOR and metabolic regulation of conventional and regulatory T cells.mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.Ionizing Radiation Impairs T Cell Activation by Affecting Metabolic Reprogramming.The RNA-binding protein HuR is essential for the B cell antibody response.G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondriaT helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.The mTOR Complex Controls HIV Latency.Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation.Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming.Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewalAutophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis.The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation.Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.Amino acid auxotrophy as a system of immunological control nodes.The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytesConditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium.Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.Nutrient and Metabolic Sensing in T Cell Responses.Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment.MYC in Regulating Immunity: Metabolism and Beyond.Amino-acid transporters in T-cell activation and differentiation.Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis.
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T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
T cell exit from quiescence an ...... iated metabolic reprogramming.
@en
T cell exit from quiescence an ...... iated metabolic reprogramming.
@nl
type
label
T cell exit from quiescence an ...... iated metabolic reprogramming.
@en
T cell exit from quiescence an ...... iated metabolic reprogramming.
@nl
prefLabel
T cell exit from quiescence an ...... iated metabolic reprogramming.
@en
T cell exit from quiescence an ...... iated metabolic reprogramming.
@nl
P2093
P2860
P1433
P1476
T cell exit from quiescence an ...... iated metabolic reprogramming.
@en
P2093
David A Guertin
Geoffrey Neale
Peer W F Karmaus
Peter Vogel
Richard F Lamb
Sharad Shrestha
P2860
P304
P356
10.1016/J.IMMUNI.2013.09.015
P407
P577
2013-12-05T00:00:00Z