Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices?
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Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channelsHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsThe cardiac conduction systemEngineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies.Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Ca²⁺-dependent phosphorylation of Ca²⁺ cycling proteins generates robust rhythmic local Ca²⁺ releases in cardiac pacemaker cells.Induced Pluripotent Stem Cell-Derived Cardiomyocytes Provide In Vivo Biological Pacemaker FunctionQuantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs.Optogenetics for in vivo cardiac pacing and resynchronization therapies.Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking.Genetically engineered excitable cardiac myofibroblasts coupled to cardiomyocytes rescue normal propagation and reduce arrhythmia complexity in heterocellular monolayersThe pathology and treatment of cardiac arrhythmias: focus on atrial fibrillationSHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability.Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling.Cardiac arrhythmia and heart failure: From bench to bedsideCell and gene therapy for arrhythmias: Repair of cardiac conduction damageBiological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block.Sustained Delivery Growth Factors with Polyethyleneimine-Modified Nanoparticles Promote Embryonic Stem Cells Differentiation and Liver Regeneration.Engineering prokaryotic channels for control of mammalian tissue excitabilityRegenerative therapies in electrophysiology and pacing: introducing the next steps.Nonviral gene therapy targeting cardiovascular system.Pacing the Heart with Genes: Recent Progress in Biological Pacing.Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins.Forced fusion of human ventricular scar cells with cardiomyocytes suppresses arrhythmogenicity in a co-culture model.Structural and functional plasticity in long-term cultures of adult ventricular myocytesPericardial approach for cardiac therapies: old practice with new ideas.Na(+) current expression in human atrial myofibroblasts: identity and functional roles.Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells.Translational medicine. Improving cardiac rhythm with a biological pacemaker.Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study.Genetic suppression of Gαs protein provides rate control in atrial fibrillation.Insights into sick sinus syndrome from an inducible mouse model.Comparison of mouse brown and white adipose‑derived stem cell differentiation into pacemaker‑like cells induced by TBX18 transduction.Optically Controlled Oscillators in an Engineered Bioelectric Tissue
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P2860
Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Biological therapies for cardi ...... lls replace drugs and devices?
@en
Biological therapies for cardi ...... lls replace drugs and devices?
@nl
type
label
Biological therapies for cardi ...... lls replace drugs and devices?
@en
Biological therapies for cardi ...... lls replace drugs and devices?
@nl
prefLabel
Biological therapies for cardi ...... lls replace drugs and devices?
@en
Biological therapies for cardi ...... lls replace drugs and devices?
@nl
P1433
P1476
Biological therapies for cardi ...... lls replace drugs and devices?
@en
P2093
Eduardo Marbán
Hee Cheol Cho
P304
P356
10.1161/CIRCRESAHA.109.212936
P577
2010-03-01T00:00:00Z