Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations.
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The role of MDM2 and MDM4 in breast cancer development and prevention.Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway.Targeting Mdmx to treat breast cancers with wild-type p53.Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapyp53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.Wip1 phosphatase in breast cancer.p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX proteinEffect of saw palmetto extract on PI3K cell signaling transduction in human glioma.The Role of MDM2 in Promoting Genome Stability versus Instability.The fate of murine double minute X (MdmX) is dictated by distinct signaling pathways through murine double minute 2 (Mdm2).MDMX is a prognostic factor for non-small cell lung cancer and regulates its sensitivity to cisplatin.The Roles of MDM2 and MDMX in Cancer.Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
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Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 25 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Amplification of Mdmx and over ...... ubstituting for p53 mutations.
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Amplification of Mdmx and over ...... ubstituting for p53 mutations.
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type
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Amplification of Mdmx and over ...... ubstituting for p53 mutations.
@en
Amplification of Mdmx and over ...... ubstituting for p53 mutations.
@nl
prefLabel
Amplification of Mdmx and over ...... ubstituting for p53 mutations.
@en
Amplification of Mdmx and over ...... ubstituting for p53 mutations.
@nl
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Amplification of Mdmx and over ...... ubstituting for p53 mutations.
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Qingyong Meng
Xiaojuan Wu
Zhishuang Li
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10.1186/1746-1596-9-71
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2014-03-25T00:00:00Z
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P6179
1001552030