Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
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Interindividual epigenetic variation in ABCB1 promoter and its relationship with ABCB1 expression and function in healthy Chinese subjectsInfluence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.Psychotropic drug-drug interactions involving P-glycoprotein.Pharmacokinetic drug interactions involving Ginkgo biloba.P-glycoprotein Inhibition for Optimal Drug Delivery.Suitability of digoxin as a P-glycoprotein probe: implications of other transporters on sensitivity and specificity.Clinical determinants of calcineurin inhibitor disposition: a mechanistic review.The putative P-gp inhibitor telmisartan does not affect the transcellular permeability and cellular uptake of the calcium channel antagonist verapamil in the P-glycoprotein expressing cell line MDCK II MDR1.Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transportersQuinidine as an ABCB1 probe for testing drug interactions at the blood-brain barrier: an in vitro in vivo correlation study.Calcein assay: a high-throughput method to assess P-gp inhibition.Effects of Gingko biloba extract on tissue distribution of fluoxetine and venlafaxine in rats.An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects.Evaluation of Proposed In Vivo Probe Substrates and Inhibitors for Phenotyping Transporter Activity in Humans.Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients.Effect of genistein on the activities of cytochrome P450 3A and P-glycoprotein in Chinese healthy participants.Clarification of P-glycoprotein inhibition-related drug-drug interaction risks based on a literature search of the clinical information.Pharmacokinetic and pharmacodynamic interaction of nadolol with itraconazole, rifampicin and grapefruit juice in healthy volunteers.Absence of pharmacokinetic interaction between roflumilast and digoxin in healthy adults.Combined Influence of Genetic Polymorphism and DNA Methylation on ABCB1 Expression and Function in Healthy Chinese Males.
P2860
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P2860
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@en
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@nl
type
label
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@en
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@nl
prefLabel
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@en
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@nl
P2093
P2860
P1476
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
@en
P2093
Anne N Nafziger
Joseph D Ma
Joseph S Bertino
Keola K Beale
Meghana Trivedi
Shirley M Tsunoda
P2860
P304
P356
10.2165/11318000-000000000-00000
P577
2010-04-01T00:00:00Z
P6179
1013496208