Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
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Epigenetics and agingAutophagy: a druggable process that is deregulated in aging and human diseaseThe search for antiaging interventions: from elixirs to fasting regimensThe many ways to age for a single yeast cellAutophagy in malignant transformation and cancer progressionConcise Review: Energy Metabolites: Key Mediators of the Epigenetic State of PluripotencyEmerging strategies to effectively target autophagy in cancerSending Out an SOS: Mitochondria as a Signaling HubCommunications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological AgingTranscriptional and epigenetic regulation of autophagy in agingEssential role for autophagy in life span extensionMitochondrial health, the epigenome and healthspanProgrammed cell death 50 (and beyond)Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populationsAcetyl-CoA synthetase is a conserved regulator of autophagy and life span.Coffee induces autophagy in vivoAkt-dependent metabolic reprogramming regulates tumor cell histone acetylationAging and energetics' 'Top 40' future research opportunities 2010-2013.Metabolic control of autophagyAntitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase.Mechanisms of In Vivo Ribosome Maintenance Change in Response to Nutrient Signals.Protein acetylation and acetyl coenzyme a metabolism in budding yeastProtein and amino acid restriction, aging and disease: from yeast to humans.Spermidine induces autophagy by inhibiting the acetyltransferase EP300.Ketogenesis prevents diet-induced fatty liver injury and hyperglycemiaLifespan extension by methionine restriction requires autophagy-dependent vacuolar acidificationFrom inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?Mitochondrial maintenance failure in aging and role of sexual dimorphism.Interventions to Slow Aging in Humans: Are We Ready?The effects of age and dietary restriction on the tissue-specific metabolome of Drosophila.Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivoThe Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing.Transcriptome-wide microRNA and target dynamics in the fat body during the gonadotrophic cycle of Aedes aegyptiLysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.The age-associated loss of ischemic preconditioning in the kidney is accompanied by mitochondrial dysfunction, increased protein acetylation and decreased autophagy.Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse.The conserved role of protein restriction in aging and diseaseGlutamine Modulates Macrophage LipotoxicityLack of mitochondria-generated acetyl-CoA by pyruvate dehydrogenase complex downregulates gene expression in the hepatic de novo lipogenic pathway.
P2860
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P2860
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@en
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@nl
type
label
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@en
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@nl
prefLabel
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@en
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@nl
P2093
P2860
P50
P1433
P1476
Nucleocytosolic depletion of t ...... tophagy and prolongs lifespan.
@en
P2093
Adrian Sprenger
Aleksandra Andryushkova
Alexandra Harger
Anuradha Bhukel
Christoph Magnes
Christoph Ruckenstuhl
Claudia Moser
Evelyne Jany
Federico Pietrocola
Frank Madeo
P2860
P304
P356
10.1016/J.CMET.2014.02.010
P50
P577
2014-03-01T00:00:00Z