Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
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A model-based approach to predict longitudinal HbA1c, using early phase glucose data from type 2 diabetes mellitus patients after anti-diabetic treatment.Identification of the mechanism of action of a glucokinase activator from oral glucose tolerance test data in type 2 diabetic patients based on an integrated glucose-insulin model.Influence of Meals and Glycemic Changes on QT Interval Dynamics.A Comprehensive Review of Novel Drug-Disease Models in Diabetes Drug Development.Application of the integrated glucose-insulin model for cross-study characterization of T2DM patients on metformin background treatment.Exploring inductive linearization for pharmacokinetic-pharmacodynamic systems of nonlinear ordinary differential equations.The Effects of a GLP-1 Analog on Glucose Homeostasis in Type 2 Diabetes Mellitus Quantified by an Integrated Glucose Insulin Model.Dose selection using a semi-mechanistic integrated glucose-insulin-glucagon model: designing phase 2 trials for a novel oral glucokinase activator.Modeling of 24-hour glucose and insulin profiles in patients with type 2 diabetes mellitus treated with biphasic insulin aspart.Model-Based Evaluation of Proximal Sodium Reabsorption Through SGLT2 in Health and Diabetes and the Effect of Inhibition With Canagliflozin.Pharmacokinetic and Pharmacodynamic Drug Interaction Study of Piragliatin, a Glucokinase Activator, and Glyburide, a Sulfonylurea, in Type 2 Diabetic Patients.Exploratory effects of a strong CYP3A inhibitor (ketoconazole), a strong CYP3A inducer (rifampicin), and concomitant ethanol on piragliatin pharmacokinetics and pharmacodynamics in type 2 diabetic patients.Effects of piragliatin, a glucokinase activator, on fasting and postprandial plasma glucose in patients with type 2 diabetes mellitus.Lack of Potential Pharmacokinetic and Pharmacodynamic Interactions Between Piragliatin, a Glucokinase Activator, and Simvastatin in Patients With Type 2 Diabetes Mellitus.Assessment of glycemic response to an oral glucokinase activator in a proof of concept study: application of a semi-mechanistic, integrated glucose-insulin-glucagon model.
P2860
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P2860
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 10 March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@en
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@nl
type
label
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@en
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@nl
prefLabel
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@en
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@nl
P2093
P2860
P921
P356
P1476
Modeling of 24-hour glucose and insulin profiles of patients with type 2 diabetes.
@en
P2093
Mats O Karlsson
Nicolas Frey
Petra M Jauslin
P2860
P304
P356
10.1177/0091270010362536
P577
2010-03-10T00:00:00Z