Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. - Wikidata - awgldk - TriplyDB

Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.

Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.

http://www.wikidata.org/entity/Q37707832

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QSOX1 inhibits autophagic flux in breast cancer cells Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma Cell Death Conversion under Hypoxic Condition in Tumor Development and Therapy Targeting autophagy in cancer management - strategies and developments Transglutaminase is a tumor cell and cancer stem cell survival factor Development of autophagy inducers in clinical medicine Autophagy, autophagy-associated adaptive immune responses and its role in hematologic malignancies Roles of autophagy induced by natural compounds in prostate cancer Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1 EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species 2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells A role for Atg8-PE deconjugation in autophagosome biogenesis Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy.Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells.Antagonism of tumoral prolactin receptor promotes autophagy-related cell death.Hypoxia Induces autophagic cell death through hypoxia-inducible factor 1α in microglia Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer.Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization.Ibrutinib, a Bruton's tyrosine kinase inhibitor, exhibits antitumoral activity and induces autophagy in glioblastoma.20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.Autophagy-regulating small molecules and their therapeutic applications.Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells.Microautophagy: lesser-known self-eating.The importance of autophagy regulation in breast cancer development and treatment.Radiation hormesis: Autophagy and other cellular mechanisms.MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin.Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells.Suppression of chloride channel 3 expression facilitates sensitivity of human glioma U251 cells to cisplatin through concomitant inhibition of Akt and autophagy.

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Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.

http://www.wikidata.org/entity/Q37707832

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 26 April 2010

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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type

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Targeting the prodeath and pro ...... rapeutic strategies in cancer.

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Bulent Ozpolat

http://www.w3.org/2001/XMLSchema#string

Gabriel Lopez-Berestein

http://www.w3.org/2001/XMLSchema#string

Ibrahim Tekedereli

http://www.w3.org/2001/XMLSchema#string

Kevin N Dalby

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P2860

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

Inhibition of macroautophagy triggers apoptosis

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

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322-329

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scholarly article

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10.4161/AUTO.6.3.11625

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3

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6

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2010-04-26T00:00:00Z

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41910558

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20224296

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2914492

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