The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds.
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Pathophysiological mechanisms of death resistance in colorectal carcinomaNovel insights for high mobility group box 1 protein-mediated cellular immune response in sepsis: A systemic reviewIncreasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular AscorbateMultiple sclerosis: molecular mechanisms and therapeutic opportunitiesEthyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuriesThe involvement of cholesterol in sepsis and tolerance to lipopolysaccharide highlighted by the transcriptome analysis of zebrafish (Danio rerio)Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammationp-Hydroxyphenylpyruvate, an intermediate of the Phe/Tyr catabolism, improves mitochondrial oxidative metabolism under stressing conditions and prolongs survival in rats subjected to profound hemorrhagic shockEthyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood CellsEthyl Pyruvate: An Anti-Microbial Agent that Selectively Targets Pathobionts and BiofilmsHydrogen peroxide detoxification is a key mechanism for growth of ammonia-oxidizing archaeaThe reactivity of α-oxoaldehyde with reactive oxygen species in diabetes complications.Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice.HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma.Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the ratRemediation of hemorrhagic shock-induced intestinal barrier dysfunction by treatment with diphenyldihaloketones EF24 and CLEFMAAlgogenic substances and metabolic status in work-related Trapezius Myalgia: a multivariate explorative study.The salutary effects of diphenyldifluoroketone EF24 in liver of a rat hemorrhagic shock modelBeneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat.Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats.Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion.Combination treatment with ethyl pyruvate and IGF-I exerts neuroprotective effects against brain injury in a rat model of neonatal hypoxic-ischemic encephalopathyEffects of ethyl pyruvate on leukocyte-endothelial interactions in the mesenteric microcirculation during early sepsis treatment.Increased Interstitial Concentrations of Glutamate and Pyruvate in Vastus Lateralis of Women with Fibromyalgia Syndrome Are Normalized after an Exercise Intervention - A Case-Control Study.Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment.Ethyl pyruvate attenuates formalin-induced inflammatory nociception by inhibiting neuronal ERK phosphorylation.Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells.Pyruvate treatment attenuates cerebral metabolic depression and neuronal loss after experimental traumatic brain injuryIntratracheal instillation of ethyl pyruvate nanoparticles prevents the development of shunt-flow-induced pulmonary arterial hypertension in a rat model.Ethyl pyruvate attenuates murine allergic rhinitis partly by decreasing high mobility group box 1 release.Pharmacologic suppression of inflammation by a diphenyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival.Impact of ethyl pyruvate on Adriamycin-induced cardiomyopathy in rats.HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells.Effects of ethyl pyruvate on cardiac function recovery and apoptosis reduction after global cold ischemia and reperfusionPharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.The glial scar in spinal cord injury and repair.The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction.Decreased inflammatory responses of human lung epithelial cells after ethanol exposure are mimicked by ethyl pyruvate.
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P2860
The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The biochemical basis for the ...... yruvate and related compounds.
@en
The biochemical basis for the ...... yruvate and related compounds.
@nl
type
label
The biochemical basis for the ...... yruvate and related compounds.
@en
The biochemical basis for the ...... yruvate and related compounds.
@nl
prefLabel
The biochemical basis for the ...... yruvate and related compounds.
@en
The biochemical basis for the ...... yruvate and related compounds.
@nl
P1476
The biochemical basis for the ...... yruvate and related compounds.
@en
P2093
Kenneth K Kao
Mitchell P Fink
P304
P356
10.1016/J.BCP.2010.03.007
P407
P577
2010-03-15T00:00:00Z