Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.
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The paracaspase MALT1: biological function and potential for therapeutic inhibitionLinear ubiquitination signals in adaptive immune responsesMechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3Molecular basis for specificity of the Met1-linked polyubiquitin signalLinear ubiquitination in immunityTargeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell LymphomaThe CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growthThe paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.Protein ubiquitination in lymphoid malignancies.B-cell receptor signaling in diffuse large B-cell lymphoma.TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway ActivationAssociation of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin LymphomaSystems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin InteractionPosttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain FormationRING finger protein 31 promotes p53 degradation in breast cancer cells.CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies.Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma.A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.Met1-linked ubiquitination in immune signalling.Ubiquitination in disease pathogenesis and treatment.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination.Roles of the NF-κB Pathway in B-Lymphocyte Biology.RNF183 promotes proliferation and metastasis of colorectal cancer cells via activation of NF-κB-IL-8 axis.The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex.Germline mutations predisposing to diffuse large B-cell lymphoma.The importance of regulatory ubiquitination in cancer and metastasis.Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis.Linear ubiquitin chains: enzymes, mechanisms and biologyMolecular Pathways: The Balance between Cancer and the Immune System Challenges the Therapeutic Specificity of Targeting Nuclear Factor-κB Signaling for Cancer TreatmentSHARPIN controls the development of regulatory T cells.Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling.SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC).MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia.Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.Genetics of diffuse large B cell lymphoma.
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Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Essential role of the linear u ...... y rare germline polymorphisms.
@en
Essential role of the linear u ...... y rare germline polymorphisms.
@nl
type
label
Essential role of the linear u ...... y rare germline polymorphisms.
@en
Essential role of the linear u ...... y rare germline polymorphisms.
@nl
prefLabel
Essential role of the linear u ...... y rare germline polymorphisms.
@en
Essential role of the linear u ...... y rare germline polymorphisms.
@nl
P2093
P2860
P50
P1433
P1476
Essential role of the linear u ...... y rare germline polymorphisms.
@en
P2093
Adrian Wiestner
Amanda Whiting
Andreas Rosenwald
Federico Bernal
George W Wright
German Ott
James R Cook
Joseph Mitala
Kazuhiro Iwai
P2860
P304
P356
10.1158/2159-8290.CD-13-0915
P50
P577
2014-02-03T00:00:00Z