Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
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Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currentsMolecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels.Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptorsThe familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cellsThe importance of occupancy rather than affinity of CaV(beta) subunits for the calcium channel I-II linker in relation to calcium channel functionHIV, opiates, and enteric neuron dysfunctionBinding of G alpha(o) N terminus is responsible for the voltage-resistant inhibition of alpha(1A) (P/Q-type, Ca(v)2.1) Ca(2+) channelsEvidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channelsNeurotransmitter modulation of small-conductance Ca2+-activated K+ channels by regulation of Ca2+ gatingDifferential modulation of N-type 1B and P/Q-type 1A calcium channels by different G protein subunit isoformsMultiple neurological abnormalities in mice deficient in the G protein GoThe ß subunit of voltage-gated Ca2+ channelsRole of voltage-gated calcium channels in ascending pain pathwaysTargeting chronic and neuropathic pain: the N-type calcium channel comes of age.Regulation of high-voltage-activated Ca(2+) channel function, trafficking, and membrane stability by auxiliary subunits.Modulating modulation.Stargazin modulates neuronal voltage-dependent Ca(2+) channel Ca(v)2.2 by a Gbetagamma-dependent mechanism.Elementary events underlying voltage-dependent G-protein inhibition of N-type calcium channels.Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.Mechanisms of modulation of voltage-dependent calcium channels by G proteins.Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition.G protein modulation of CaV2 voltage-gated calcium channelsAnalgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits.Decay of prepulse facilitation of N type calcium channels during G protein inhibition is consistent with binding of a single Gbeta subunitμ Opioid Receptor Expression after Morphine Administration Is Regulated by miR-212/132 Cluster.Molecular regulation of voltage-gated Ca2+ channels.Differential occurrence of reluctant openings in G-protein-inhibited N- and P/Q-type calcium channelsCustom distinctions in the interaction of G-protein beta subunits with N-type (CaV2.2) versus P/Q-type (CaV2.1) calcium channelsUnique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation.Regulation of Ca(V)2 calcium channels by G protein coupled receptors.Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors.Molecular mechanisms of opioid receptor-dependent signaling and behavior.Origin of the voltage dependence of G-protein regulation of P/Q-type Ca2+ channels.Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses.Targeting voltage-gated calcium channels for neuropathic pain management.Cavbeta-subunit displacement is a key step to induce the reluctant state of P/Q calcium channels by direct G protein regulationDifferential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activationActivation of μ-opioid receptors inhibits calcium-currents in the vestibular afferent neurons of the rat through a cAMP dependent mechanism.Calcium channel functions in pain processing
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P2860
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@en
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@nl
type
label
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@en
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@nl
prefLabel
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@en
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@nl
P2093
P2860
P356
P1476
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.4.1486
P407
P577
1996-02-01T00:00:00Z