Complexity and simplicity in the biosynthesis of enediyne natural products.
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Solution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisStructure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19Strain Prioritization and Genome Mining for Enediyne Natural ProductsA sea of biosynthesis: marine natural products meet the molecular age.Synthesis of the carboline disaccharide domain of shishijimicin A.Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.Engineered production of cancer targeting peptide (CTP)-containing C-1027 in Streptomyces globisporus and biological evaluationCrystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics.The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics.Iterative type I polyketide synthases involved in enediyne natural product biosynthesis.Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes.Environmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis.Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropicaBiochemical determination of enzyme-bound metabolites: preferential accumulation of a programmed octaketide on the enediyne polyketide synthase CalE8Access to Acyclic Z-Enediynes by Alkyne Trimerization: Cooperative Bimetallic Catalysis Using Air as the Oxidant.Weapons in disguise--activating mechanisms and protecting group chemistry in nature.
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Complexity and simplicity in the biosynthesis of enediyne natural products.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 February 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Complexity and simplicity in the biosynthesis of enediyne natural products.
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Complexity and simplicity in the biosynthesis of enediyne natural products.
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type
label
Complexity and simplicity in the biosynthesis of enediyne natural products.
@en
Complexity and simplicity in the biosynthesis of enediyne natural products.
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prefLabel
Complexity and simplicity in the biosynthesis of enediyne natural products.
@en
Complexity and simplicity in the biosynthesis of enediyne natural products.
@nl
P2860
P356
P1476
Complexity and simplicity in the biosynthesis of enediyne natural products.
@en
P2093
Zhao-Xun Liang
P2860
P304
P356
10.1039/B908165H
P577
2010-02-18T00:00:00Z