Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease.
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Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways.Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemA small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophyModulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseasesAntileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions.The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solutionPrion degradation pathways: Potential for therapeutic intervention.Nuclear factor erythroid-2 related factor 2 (Nrf2)-mediated protein quality control in cardiomyocytes.Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.Proteostasis of Huntingtin in Health and DiseaseCardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy.The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.Sulforaphane is anticonvulsant and improves mitochondrial function.Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer's Disease.The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease
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Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
@en
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
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type
label
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
@en
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
@nl
prefLabel
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
@en
Sulforaphane enhances proteaso ...... gent for Huntington's disease.
@nl
P2093
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Sulforaphane enhances proteaso ...... agent for Huntington's disease
@en
P2093
Casey L Hettinger
Hongmin Wang
Khosrow Rezvani
Xuejun Wang
Yanying Liu
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P304
P356
10.1111/JNC.12647
P407
P50
P577
2014-01-18T00:00:00Z