Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
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G-quadruplexes and helicasesRoles of DNA helicases in the maintenance of genome integrityYeast Pif1 accelerates annealing of complementary DNA strands.The Causes and Consequences of Topological Stress during DNA ReplicationG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomePfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome IntegritySingle-Molecule Pull-Down FRET to Dissect the Mechanisms of Biomolecular MachinesSingle-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicasesRPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome endsPIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes.Ataxin-2: From RNA Control to Human Health and DiseaseRecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATPMechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structuresThe Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.A parallel quadruplex DNA is bound tightly but unfolded slowly by pif1 helicase.G-quadruplexes significantly stimulate Pif1 helicase-catalyzed duplex DNA unwinding.A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands.The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres.Borrowing nuclear DNA helicases to protect mitochondrial DNA.BLM unfolds G-quadruplexes in different structural environments through different mechanismsATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity.Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.Single-molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase.Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase.Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development.Yeast Helicase Pif1 Unwinds RNA:DNA Hybrids with Higher Processivity than DNA:DNA Duplexes.A Monomer of Pif1 Unwinds Double-Stranded DNA and It Is Regulated by the Nature of the Non-Translocating Strand at the 3'-EndPif1 is a force-regulated helicaseChemo-mechanical pushing of proteins along single-stranded DNA.A Comparative Study of G-Quadruplex Unfolding and DNA Reeling Activities of Human RECQ5 HelicaseG-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction.G-quadruplex recognition and remodeling by the FANCJ helicaseRHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis.Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding.Single-molecule sorting of DNA helicases.R-loops highlight the nucleus in ALS.Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids.A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4.Getting it done at the ends: Pif1 family DNA helicases and telomeres.Molecular watchdogs on genome patrol
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Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 April 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
@en
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
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type
label
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
@en
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
@nl
prefLabel
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
@en
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.
@nl
P2860
P50
P356
P1433
P1476
Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA
@en
P2093
Jichuan Zhang
Virginia A Zakian
P2860
P304
P356
10.7554/ELIFE.02190
P407
P577
2014-04-29T00:00:00Z