Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects. - Wikidata - awgldk - TriplyDB

Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects.

Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects.

http://www.wikidata.org/entity/Q37727959

about

A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.Ribonuclease-Activated Cancer Prodrug.AZT 5'-Phosphonates: Achievements and Trends in the Treatment and Prevention of HIV Infection New dinucleoside phosphonate derivatives as prodrugs of 3'-azido-3'-deoxythymidine and β-L-2',3'-dideoxy-3'-thiacytidine: synthesis and anti-HIV properties.Synthesis and anti-HIV properties of new carbamate prodrugs of AZT.5'-phosphonate derivatives of 2',3'-dideoxy-3'-thiacytidine as new anti-HIV prodrugs.Chalcogenozidovudine Derivatives With Antitumor Activity: Comparative Toxicities in Cultured Human Mononuclear Cells.Cs2 CO3 -Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes.

P2860

Q35174634-8C8B80A7-999D-4E4B-AAA0-89525A563E07 Q35964892-08D43473-362E-463F-BC25-962FBB1E4B04 Q37358511-5E113894-9BAB-4C00-8702-AEA0BFD0ED5F Q39012536-B561B594-AE52-4F37-A493-D0E39B99AAB1 Q39283483-07621625-B27F-4E98-B929-FC596EA72331 Q39553451-4EB7DBA8-4244-4FC8-A932-D7B79F2B90DC Q46284143-791847C3-7BF3-4A84-800F-43F3BCE033BB Q48324069-198C21B2-1787-45A2-B006-EF1B52463086

P2860

Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects.

http://www.wikidata.org/entity/Q37727959

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on June 2010

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@en

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@nl

type

label

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@en

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@nl

prefLabel

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@en

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@nl

P1433

Q37727959-0B19A73B-49C0-4291-938E-BDC2D654F423

P1476

Q37727959-01EEFA75-B02F-46D7-98E3-19F6943E60FA

P2093

Q37727959-537DAAE0-257A-4A9B-8B3A-69E9940BF538

Q37727959-E17F279C-28B6-47A3-8DB2-9951B36DEB89

Q37727959-FB1348CE-3AFF-4D6E-A8D1-3BDF3C2E14C0

P2860

Q37727959-013860F6-1ED5-415B-B7F3-35DADC209C99

Q37727959-11D0EC6E-5E05-4847-9124-AE4D0BFC292C

Q37727959-15523AED-31B8-4AAE-8DBD-7ED32BBF5288

Q37727959-1F99D242-C379-4AC7-85C3-2C2688C213A7

Q37727959-2238D107-281B-4893-BD92-5BA6DF462277

Q37727959-26FDD7F9-6731-4656-8651-608C7AA89BDD

Q37727959-31F6E4DF-94D7-42C1-BE96-E47A438E4395

Q37727959-395D36E3-F808-4F46-951A-630A18D8DABB

Q37727959-3D02F33C-0883-42A0-B102-1233F53A3817

Q37727959-43CC72D9-D29B-4BD5-9918-F84F7E886A3F

P304

Q37727959-10C14BCC-E838-4316-947D-95DEF0613B06

P31

Q37727959-80770997-957B-4411-896E-201E7765482B

P356

Q37727959-1676D6C2-70EC-4365-AAD2-CC6C99C167C5

P407

Q37727959-4DF83D5A-AEE7-41AC-9CB6-961EA1A387D6

P433

Q37727959-8DFA4FD5-8E89-4497-9200-CE1669016219

P478

Q37727959-E79E362B-9BFE-4848-8B82-5A8451EEE77E

P577

Q37727959-3518B331-A6F2-464E-909E-E9EB06B30441

P5875

Q37727959-58D7D63D-084B-43CE-AE47-5B550F9D4200

P698

Q37727959-2DEB4F76-9393-4031-81E5-68C4989835CB

P356

17425251003713501

P1433

Expert Opinion on Drug Metabolism & Toxicology

P1476

Anti-HIV therapy with AZT prod ...... , current state and prospects.

@en

P2093

Anastasiya Khandazhinskaya

http://www.w3.org/2001/XMLSchema#string

Elena Matyugina

http://www.w3.org/2001/XMLSchema#string

Elena Shirokova

http://www.w3.org/2001/XMLSchema#string

P2860

Antiviral prodrugs - the development of successful prodrug strategies for antiviral chemotherapy

3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

3'-Azido-3',5'-dideoxythymidine-5'-methylphosphonic acid diphosphate: synthesis and HIV-1 reverse transcriptase inhibition

5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity

Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine

Inhibition of human immunodeficiency virus type 1 replication by phosphonoformate esters of 3'-azido-3'-deoxythymidine

Synthesis and evaluation of novel ether lipid nucleoside conjugates for anti-HIV-1 activity

Synthesis and biological evaluation of dinucleoside methylphosphonates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxycytidine

Nature, time course and dose dependence of zidovudine-related side effects: results from the Multicenter Canadian Azidothymidine Trial

P304

701-714

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1517/17425251003713501

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P577

2010-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

43097512

http://www.w3.org/2001/XMLSchema#string

P698

20380483

http://www.w3.org/2001/XMLSchema#string