The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase.
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Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particlesUSP11 stabilizes HPV-16E7 and further modulates the E7 biological activityNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligaseSCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigenDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerThe association of mammalian DREAM complex and HPV16 E7 proteinsThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiologyThe influence of proteasome inhibitor MG132, external radiation, and unlabeled antibody on the tumor uptake and biodistribution of (188)re-labeled anti-E6 C1P5 antibody in cervical cancer in miceTargeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.The emerging role of the COP9 signalosome in cancer.Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7.Cullins and cancer.Radioimmunotherapy of experimental head and neck squamous cell carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16 positive HNSCC cell lineRadioimmunotherapy with an antibody to the HPV16 E6 oncoprotein is effective in an experimental cervical tumor expressing low levels of E6.Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein.An RNA aptamer provides a novel approach for the induction of apoptosis by targeting the HPV16 E7 oncoprotein.Nonconserved lysine residues attenuate the biological function of the low-risk human papillomavirus E7 proteinHuman papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressorViral modulators of cullin RING ubiquitin ligases: culling the host defense.Human papillomavirus E7 induces rereplication in response to DNA damageThe Role of F-Box Proteins during Viral Infection.The papillomavirus E7 proteins.The human papillomavirus E7 oncoprotein.Ubiquitin control of S phase: a new role for the ubiquitin conjugating enzyme, UbcH7.Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.Viral takeover of the host ubiquitin system.E3 ubiquitin ligases and human papillomavirus-induced carcinogenesis.The role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology.Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator.The PTPN14 Tumor Suppressor Is a Degradation Target of Human Papillomavirus E7.Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis.Pathway analysis of cervical cancer genome-wide association study highlights the MHC region and pathways involved in response to infection.
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The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@en
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@nl
type
label
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@en
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@nl
prefLabel
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@en
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@nl
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P2860
P1433
P1476
The papillomavirus E7 oncoprot ...... and Skp2-containing E3 ligase.
@en
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Anna Kalinina
Keiichi I Nakayama
Keiko Nakayama
Kwang-Jin Oh
Srilata Bagchi
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P304
P356
10.1128/JVI.78.10.5338-5346.2004
P407
P577
2004-05-01T00:00:00Z